Hs02406829_cn

• Gene Symbol: NDRG2
• Assay Reference Genome Location: Chr.14:21043496 on build GRCh38
• Cytoband: 14q11.2

Target Gene Details

• Entrez Gene ID: 57447
• Gene Name: NDRG family member 2
• Gene Aliases: SYLD
• Location: Chr.14:21016763-21070872 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
NDRG2	NM_001282211.1			NP_001269140.1
	AK293514.1

Target Gene Details

• Entrez Gene ID: 84659
• Gene Name: ribonuclease A family member 7
• Gene Aliases: RAE1
• Location: Chr.14:21042226-21044233 on Build GRCh38
• Assay Gene Location: Within Exon 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
RNASE7	NM_032572.3	2	761	NP_115961.2
	AJ131212.1	1	504	CAC20410.1
	AJ306608.1	2	671	CAC84462.1
	AJ306609.1	2	671	CAC84457.1
	AJ306610.1	2	671	CAC84458.1
	AK292697.1	2	761
	AY170392.1	2	735	AAO12510.1
	AY359097.1	2	603	AAQ89455.1
	BC074960.2			AAH74960.1
	BC112334.1	2	599	AAI12335.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv428293	Chr.14:20747949 - 21063624 on Build GRCh38	Gain+Loss	RNASE1 ECRP METTL17 SLC39A2 EDDM3A RNASE3 NDRG2 RNASE8 RNASE13 RNASE2 MIR6717 LOC101929718 ARHGEF40 EDDM3B RNASE6 RNASE7 TPPP2
nsv826882	Chr.14:21042862 - 21136042 on Build GRCh38	Gain	ARHGEF40 ZNF219 TMEM253 NDRG2 RNASE8 RNASE7
nsv832740	Chr.14:20863901 - 21076893 on Build GRCh38	Gain	ECRP METTL17 SLC39A2 RNASE3 NDRG2 RNASE8 RNASE13 RNASE2 MIR6717 LOC101929718 ARHGEF40 RNASE7 TPPP2
nsv1039369	Chr.14:21030895 - 21062142 on Build GRCh38	Loss	ARHGEF40 NDRG2 RNASE8 RNASE13 RNASE7 TPPP2

More Information

• Set Membership: Intragenic, Exonic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

serine protease

Gene Ontology Categories:

Process(es)

negative regulation of cytokine production
signal transduction
regulation of vascular endothelial growth factor production
Wnt signaling pathway
substantia nigra development
cell differentiation
negative regulation of smooth muscle cell proliferation
negative regulation of ERK1 and ERK2 cascade
regulation of platelet-derived growth factor production
response to bacterium
antibacterial humoral response
innate immune response
defense response to Gram-negative bacterium
defense response to Gram-positive bacterium
membrane disruption in other organism
RNA phosphodiester bond hydrolysis

Function(s)

molecular_function
protein binding
lipopolysaccharide binding
nucleic acid binding
endonuclease activity
ribonuclease activity
peptidoglycan binding