Hs02487797_cn

• Gene Symbol: IARS2
• Assay Reference Genome Location: Chr.1:220096164 on build GRCh38
• Cytoband: 1q41

Target Gene Details

• Entrez Gene ID: 55699
• Gene Name: isoleucyl-tRNA synthetase 2, mitochondrial
• Gene Aliases: CAGSSS, ILERS
• Location: Chr.1:220094113-220148041 on Build GRCh38
• Assay Gene Location: Within Exon 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
IARS2	NM_018060.3	2	432	NP_060530.3
	AK291432.1	2	241
	AY267462.1	2	443
	AY952883.1	2	345
	BC040376.1	2	165
	BC137438.1	2	402
	BI459732.1	2	436
	BM149097.1	2	433
	D28500.1	2	273	BAA95147.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv832636	Chr.1:219966355 - 220121010 on Build GRCh38	Loss	MIR215 BPNT1 EPRS IARS2 MIR194-1

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

aminoacyl-tRNA synthetase

Gene Ontology Categories:

Process(es)

tRNA aminoacylation for protein translation
isoleucyl-tRNA aminoacylation
regulation of translational fidelity

Function(s)

tRNA binding
aminoacyl-tRNA editing activity
isoleucine-tRNA ligase activity
ATP binding