Hs02499642_cn

• Gene Symbol: AGO4
• Assay Reference Genome Location: Chr.1:35826745 on build GRCh38
• Cytoband: 1p34.3

Target Gene Details

• Entrez Gene ID: 192670
• Gene Name: argonaute 4, RISC catalytic component
• Gene Aliases: EIF2C4
• Location: Chr.1:35807630-35857890 on Build GRCh38
• Assay Gene Location: Overlaps Intron 7 - Exon 8

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
AGO4	NM_017629.3			NP_060099.2
	XM_005270578.3			XP_005270635.1
	XM_005270579.3			XP_005270636.1
	XM_011540883.2			XP_011539185.1
	XM_011540884.2			XP_011539186.1
	XM_017000529.1			XP_016856018.1
	AB046787.1
	AL831908.1
	BC152450.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv834680	Chr.1:35660621 - 35892216 on Build GRCh38	Gain	CLSPN C1orf216 AGO4 AGO1
nsv525430	Chr.1:35776427 - 35860595 on Build GRCh38	Loss	AGO4

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

translation initiation factor

Gene Ontology Categories:

Process(es)

mRNA catabolic process
Wnt signaling pathway, calcium modulating pathway
RNA secondary structure unwinding
pre-miRNA processing
posttranscriptional gene silencing by RNA
production of miRNAs involved in gene silencing by miRNA
miRNA mediated inhibition of translation
mRNA cleavage involved in gene silencing by miRNA
miRNA loading onto RISC involved in gene silencing by miRNA
phosphatidylinositol-mediated signaling
mRNA cleavage involved in gene silencing by siRNA

Function(s)

double-stranded RNA binding
single-stranded RNA binding
protein binding
miRNA binding