Hs02504752_cn

• Gene Symbol: LIFR
• Assay Reference Genome Location: Chr.5:38476019 on build GRCh38
• Cytoband: 5p13.1

Target Gene Details

• Entrez Gene ID: 3977
• Gene Name: leukemia inhibitory factor receptor alpha
• Gene Aliases: CD118, LIF-R, SJS2, STWS, SWS
• Location: Chr.5:38474963-38606290 on Build GRCh38
• Assay Gene Location: Within Exon 25

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
LIFR	NM_001127671.1	20	9202	NP_001121143.1
	NM_002310.5	20	9034	NP_002301.1
	XM_017009462.1	20	9047	XP_016864951.1
	BX648635.1	1	3427

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3604768	Chr.5:38395532 - 38507296 on Build GRCh38	Gain	EGFLAM LIFR EGFLAM-AS2
esv3604761	Chr.5:38056637 - 38805862 on Build GRCh38	Gain	EGFLAM OSMR-AS1 LIFR LINC01265 EGFLAM-AS2 LIFR-AS1 LOC101929745 MIR3650 EGFLAM-AS4

More Information

Additional Information:

• Set Membership: Intragenic, Exonic, DGV Variation, Validated

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

cell surface receptor signaling pathway
positive regulation of cell proliferation
negative regulation of muscle cell apoptotic process
response to organic cyclic compound
cytokine-mediated signaling pathway
organ regeneration
response to cytokine
oncostatin-M-mediated signaling pathway
neuron projection morphogenesis
leukemia inhibitory factor signaling pathway
ciliary neurotrophic factor-mediated signaling pathway

Function(s)

ciliary neurotrophic factor receptor activity
leukemia inhibitory factor receptor activity
oncostatin-M receptor activity
ciliary neurotrophic factor receptor binding
protein binding
growth factor binding
cytokine binding
protein heterodimerization activity