Hs02558327_cn

• Gene Symbol: CYP1A1
• Assay Reference Genome Location: Chr.15:74722727 on build GRCh38
• Cytoband: 15q24.1

Target Gene Details

• Entrez Gene ID: 1543
• Gene Name: cytochrome P450 family 1 subfamily A member 1
• Gene Aliases: AHH, AHRR, CP11, CYP1, CYPIA1, P1-450, P450-C, P450DX
• Location: Chr.15:74719542-74725610 on Build GRCh38
• Assay Gene Location: Within Exon 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CYP1A1	NM_000499.4	2	567	NP_000490.1
	NM_001319216.1	2	570	NP_001306145.1
	NM_001319217.1	2	570	NP_001306146.1
	XM_017021953.1	2	570	XP_016877442.1
	AK223108.1	2	488	BAD96828.1
	AK223113.1	2	485	BAD96833.1
	AK310810.1	2	614
	AK313880.1	2	485
	AM233517.1
	AM233518.1
	AM233519.1	2	448
	AM233520.1	2	448
	AM236046.1	2	448
	AM236047.1
	AY310359.1	1	371	AAQ76692.1
	AY871801.1	2	454
	BC023019.1	2	452	AAH23019.1
	DA693879.1
	K03191.1	2	457	AAA52139.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv833055	Chr.15:74696003 - 74873947 on Build GRCh38	Loss	SCAMP2 MIR4513 CPLX3 MIR6882 EDC3 ULK3 CYP1A2 CYP1A1 CSK LMAN1L
esv3636907	Chr.15:74721538 - 74745196 on Build GRCh38	Loss	CYP1A1
nsv817698	Chr.15:74596822 - 74727108 on Build GRCh38	Gain	CLK3 EDC3 ARID3B CYP1A1 LOC102723750
esv2763106	Chr.15:74722123 - 74741845 on Build GRCh38	Loss	CYP1A1
nsv1121512	Chr.15:72670085 - 75273877 on Build GRCh38	Deletion	ISLR LOXL1 CYP1A1 LOXL1-AS1 LOC729739 CPLX3 FAM219B STOML1 LOC101929333 NPTN ULK3 NEO1 MIR6882 HIGD2B LOC732265 ADPGK CYP11A1 MIR6881 HCN4 CCDC33 ISLR2 COX5A ARID3B CSK SEMA7A SCAMP2 MPI NPTN-IT1 TBC1D21 BBS4 CD276 SCAMP5 REC114 LMAN1L RPP25 GOLGA6C UBL7 STRA6 UBL7-AS1 C15orf39 LOC107984728 LOC283731 ADPGK-AS1 CLK3 PML C15orf59 CYP1A2 LOC105376731 MIR4513 EDC3 C15orf59-AS1 PPCDC GOLGA6A LOC102723750

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

response to hypoxia
porphyrin-containing compound metabolic process
aging
cell proliferation
amine metabolic process
response to wounding
response to virus
response to nematode
response to herbicide
ethylene metabolic process
embryo development ending in birth or egg hatching
coumarin metabolic process
flavonoid metabolic process
response to iron(III) ion
insecticide metabolic process
drug metabolic process
dibenzo-p-dioxin catabolic process
epoxygenase P450 pathway
response to food
response to lipopolysaccharide
response to vitamin A
response to immobilization stress
vitamin D metabolic process
response to drug
9-cis-retinoic acid biosynthetic process
camera-type eye development
response to antibiotic
response to arsenic-containing substance
digestive tract development
hydrogen peroxide biosynthetic process
response to hyperoxia
oxidation-reduction process
maternal process involved in parturition
hepatocyte differentiation
demethylation
cellular response to organic cyclic compound
omega-hydroxylase P450 pathway
positive regulation of G1/S transition of mitotic cell cycle

Function(s)

monooxygenase activity
iron ion binding
protein binding
steroid hydroxylase activity
oxidoreductase activity
oxidoreductase activity, acting on diphenols and related substances as donors
flavonoid 3'-monooxygenase activity
oxygen binding
enzyme binding
heme binding
demethylase activity
aromatase activity
vitamin D 24-hydroxylase activity