Hs02608084_cn

• Gene Symbol: GFM1
• Assay Reference Genome Location: Chr.3:158666625 on build GRCh38
• Cytoband: 3q25.32

Target Gene Details

• Entrez Gene ID: 85476
• Gene Name: G elongation factor mitochondrial 1
• Gene Aliases: COXPD1, EFG, EFG1, EFGM, EGF1, GFM, hEFG1
• Location: Chr.3:158644497-158692572 on Build GRCh38
• Assay Gene Location: Within Intron 14

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
GFM1	NM_001308164.1			NP_001295093.1
	NM_001308166.1			NP_001295095.1
	NM_024996.5			NP_079272.4
	XM_006713795.1			XP_006713858.1
	AF309777.1			AAK58877.1
	AF367998.1			AAK53402.1
	AK000780.1
	AK092293.1
	AK315031.1
	BC049210.1			AAH49210.1
	KU178816.1
	KU178817.1

Target Gene Details

• Entrez Gene ID: 56925
• Gene Name: latexin
• Gene Aliases: ECI, TCI
• Location: Chr.3:158666414-158672722 on Build GRCh38
• Assay Gene Location: Within Exon 5

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
LXN	NM_020169.3	6	905	NP_064554.3
	XM_017006876.1	5	1201	XP_016862365.1
	AF087851.1	6	768	AAP97162.1
	AF282594.1	6	774	AAK69518.1
	AF282626.1	6	841	AAF82807.1
	BC005346.1	6	905	AAH05346.1
	BC008438.1	6	887	AAH08438.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2763312	Chr.3:158475723 - 158702799 on Build GRCh38	Gain	GFM1 RSRC1 RARRES1 LOC100996447 MLF1 LXN
nsv1014255	Chr.3:158641071 - 159050753 on Build GRCh38	Gain	GFM1 MFSD1 RARRES1 LOC100287290 LXN LOC105374181
nsv1004124	Chr.3:158428926 - 159090849 on Build GRCh38	Gain	GFM1 MFSD1 RSRC1 RARRES1 LOC100996447 LOC100287290 IQCJ-SCHIP1 IQCJ MLF1 LXN LOC105374181

More Information

• Set Membership: Intragenic, Exonic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

protease inhibitor

Gene Ontology Categories:

Process(es)

mitochondrial translational elongation
inflammatory response
negative regulation of endopeptidase activity
detection of temperature stimulus involved in sensory perception of pain

Function(s)

translation elongation factor activity
GTPase activity
protein binding
GTP binding
poly(A) RNA binding
metalloendopeptidase inhibitor activity
heparin binding