Hs02688105_cn

• Gene Symbol: ANAPC2
• Assay Reference Genome Location: Chr.9:137188629 on build GRCh38
• Cytoband: 9q34.3

Target Gene Details

• Entrez Gene ID: 29882
• Gene Name: anaphase promoting complex subunit 2
• Gene Aliases: APC2
• Location: Chr.9:137174784-137188605 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ANAPC2	NM_013366.3			NP_037498.1

Target Gene Details

• Entrez Gene ID: 8636
• Gene Name: SS nuclear autoantigen 1
• Gene Aliases: N14, NA-14, NA14
• Location: Chr.9:137188602-137190370 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SSNA1	NM_003731.2			NP_003722.2
	BC000864.1			AAH00864.1
	DB466912.1
	Z96932.1			CAB09660.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv616007	Chr.9:137079368 - 137240666 on Build GRCh38	Loss	MAN1B1-AS1 TMEM203 DPP7 GRIN1 SSNA1 NDOR1 SLC34A3 RNF224 LRRC26 MAN1B1 RNF208 LOC101930307 TMEM210 MIR3621 UAP1L1 CYSRT1 ANAPC2 TPRN
dgv13009n54	Chr.9:137173890 - 137327859 on Build GRCh38	Loss	TMEM203 NRARP STPG3 SSNA1 NDOR1 TUBB4B SLC34A3 RNF224 RNF208 FAM166A EXD3 C9orf173-AS1 CYSRT1 ANAPC2 TPRN TOR4A NELFB
nsv524322	Chr.9:136795692 - 137482216 on Build GRCh38	Loss	NRARP STPG3 PHPT1 FBXW5 EXD3 NOXA1 C8G PRR31 MIR4292 TPRN FUT7 NDOR1 RNF224 LCNL1 LRRC26 NSMF ENTPD2 RABL6 LOC101930307 TMEM210 C9orf173-AS1 ENTPD8 CYSRT1 C9orf142 NELFB MIR7114 TMEM203 DPP7 GRIN1 SSNA1 ABCA2 CCDC183 FAM166A NPDC1 TOR4A PNPLA7 SAPCD2 MAN1B1-AS1 C9orf172 C9orf139 TUBB4B SLC34A3 TRAF2 MAN1B1 RNF208 MAMDC4 LCN12 PTGDS MIR3621 MIR4479 UAP1L1 EDF1 ANAPC2 CLIC3 CCDC183-AS1
nsv951207	Chr.9:137136949 - 137379148 on Build GRCh38	Deletion	TMEM203 NRARP STPG3 GRIN1 SSNA1 NDOR1 TUBB4B SLC34A3 RNF224 LRRC26 RNF208 FAM166A EXD3 TMEM210 MIR3621 C9orf173-AS1 CYSRT1 ANAPC2 TPRN TOR4A NELFB
nsv1161918	Chr.9:137118319 - 137438026 on Build GRCh38	Duplication	TMEM203 NRARP STPG3 GRIN1 SSNA1 NDOR1 TUBB4B SLC34A3 RNF224 LRRC26 RNF208 FAM166A EXD3 TMEM210 NOXA1 MIR3621 C9orf173-AS1 ENTPD8 CYSRT1 ANAPC2 TPRN TOR4A NELFB
esv2761561	Chr.9:137030185 - 137191593 on Build GRCh38	Gain	SAPCD2 MAN1B1-AS1 C9orf139 DPP7 GRIN1 SSNA1 FUT7 LRRC26 MAN1B1 ENTPD2 LOC101930307 TMEM210 MIR3621 UAP1L1 NPDC1 ANAPC2
esv2422220	Chr.9:136584135 - 137350098 on Build GRCh38	Deletion	LCN6 NRARP STPG3 PHPT1 SNHG7 LCN15 FBXW5 EXD3 C8G PRR31 MIR4292 TPRN AGPAT2 FUT7 NDOR1 RNF224 LCNL1 LRRC26 ENTPD2 RABL6 LOC101930307 SNORA17B TMEM210 C9orf173-AS1 CYSRT1 MIR126 C9orf142 NELFB LCN10 TMEM203 DPP7 GRIN1 SSNA1 FAM69B EGFL7 ABCA2 CCDC183 FAM166A MIR6722 HSPC324 LOC100128593 NPDC1 LCN8 TOR4A SAPCD2 TMEM141 MAN1B1-AS1 C9orf172 C9orf139 TUBB4B SLC34A3 TRAF2 MAN1B1 RNF208 MAMDC4 LCN12 LINC01451 PTGDS MIR3621 SNORA17A MIR4479 UAP1L1 EDF1 ANAPC2 CLIC3 CCDC183-AS1

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

mitotic nuclear division
anaphase-promoting complex-dependent catabolic process
positive regulation of synaptic plasticity
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
proteasome-mediated ubiquitin-dependent protein catabolic process
positive regulation of axon extension
positive regulation of dendrite morphogenesis
cell division
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
protein K11-linked ubiquitination
positive regulation of synapse maturation
G2/M transition of mitotic cell cycle
intraciliary transport
ciliary receptor clustering involved in smoothened signaling pathway

Function(s)

ubiquitin protein ligase binding
ubiquitin protein ligase activity
protein binding
identical protein binding