Hs02721444_cn

• Gene Symbol: STK16
• Assay Reference Genome Location: Chr.2:219250289 on build GRCh38
• Cytoband: 2q35

Target Gene Details

• Entrez Gene ID: 8576
• Gene Name: serine/threonine kinase 16
• Gene Aliases: KRCT, MPSK, PKL12, TSF1
• Location: Chr.2:219245469-219250337 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 8

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
STK16	NM_001008910.2			NP_001008910.1
	NR_026909.1
	XM_011512067.2			XP_011510369.1

Target Gene Details

• Entrez Gene ID: 7277
• Gene Name: tubulin alpha 4a
• Gene Aliases: ALS22, H2-ALPHA, TUBA1
• Location: Chr.2:219249711-219254608 on Build GRCh38
• Assay Gene Location: Within Exon 5

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TUBA4A	NM_001278552.1	4	1921	NP_001265481.1
	NM_006000.2	4	1498	NP_005991.1
	XM_017004824.1			XP_016860313.1
	AK054731.1	4	1468
	AK299958.1
	BC009238.2			AAH09238.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv834543	Chr.2:219226398 - 219416430 on Build GRCh38	Loss	RESP18 MIR153-1 TUBA4B STK16 GLB1L DNAJB2 ANKZF1 ATG9A DNPEP TUBA4A PTPRN
nsv963775	Chr.2:219249827 - 219251406 on Build GRCh38	Duplication	STK16 TUBA4A
esv3893555	Chr.2:219172722 - 219273269 on Build GRCh38	Loss	TUBA4B CNPPD1 ABCB6 STK16 GLB1L FAM134A ZFAND2B ANKZF1 ATG9A TUBA4A
nsv954842	Chr.2:219250279 - 219254378 on Build GRCh38	Deletion	TUBA4B STK16 TUBA4A
nsv508885	Chr.2:219231225 - 219333602 on Build GRCh38	Insertion	RESP18 MIR153-1 TUBA4B STK16 GLB1L DNAJB2 ANKZF1 TUBA4A PTPRN

More Information

• Set Membership: Intragenic, Exonic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase, tubulin

Gene Ontology Categories:

Process(es)

transcription from RNA polymerase II promoter
peptidyl-tyrosine phosphorylation
positive regulation of transcription from RNA polymerase II promoter
protein autophosphorylation
cellular response to transforming growth factor beta stimulus
G2/M transition of mitotic cell cycle
platelet degranulation
cytoskeleton organization
microtubule-based process

Function(s)

transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
protein serine/threonine kinase activity
non-membrane spanning protein tyrosine kinase activity
protein binding
ATP binding
GTPase activity
structural constituent of cytoskeleton
GTP binding
enzyme binding