Hs02777293_cn

• Gene Symbol: CCT4
• Assay Reference Genome Location: Chr.2:61868555 on build GRCh38
• Cytoband: 2p15

Target Gene Details

• Entrez Gene ID: 10575
• Gene Name: chaperonin containing TCP1 subunit 4
• Gene Aliases: CCT-DELTA, Cctd, SRB
• Location: Chr.2:61868127-61888671 on Build GRCh38
• Assay Gene Location: Within Exon 14

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CCT4	NM_001256721.1	13	1831	NP_001243650.1
	NM_006430.3	14	1921	NP_006421.2
	AA136129.1
	AF026291.1	14	1859	AAC96010.1
	AI439570.1	1	432
	AK129860.1	14	1830
	AK290538.1	14	1888
	AK295330.1	14	1694
	AK303082.1	13	1816
	AL555753.3	1	402
	BC014676.1	7	891	AAH14676.1
	BC106933.1			AAI06934.1
	BC106934.1			AAI06935.1
	CD369623.1
	U38846.1	14	1757	AAC50384.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv582123	Chr.2:61719360 - 62324337 on Build GRCh38	Gain	FAM161A CCT4 COMMD1 MIR5192 B3GNT2
nsv582122	Chr.2:61692252 - 62020316 on Build GRCh38	Gain	FAM161A CCT4 COMMD1
nsv470467	Chr.2:61786803 - 62020316 on Build GRCh38	Gain	FAM161A CCT4 COMMD1
nsv582118	Chr.2:61431550 - 62075525 on Build GRCh38	Gain	FAM161A CCT4 COMMD1 XPO1 USP34
esv34000	Chr.2:61672382 - 62157212 on Build GRCh38	Loss	FAM161A CCT4 COMMD1

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

chaperonin

Gene Ontology Categories:

Process(es)

protein folding
binding of sperm to zona pellucida
positive regulation of telomere maintenance via telomerase
protein stabilization
positive regulation of telomerase activity
scaRNA localization to Cajal body
toxin transport
positive regulation of establishment of protein localization to telomere
positive regulation of protein localization to Cajal body
positive regulation of telomerase RNA localization to Cajal body

Function(s)

protein binding
ATP binding
poly(A) RNA binding
unfolded protein binding