Hs02811625_cn

• Gene Symbol: JCHAIN
• Assay Reference Genome Location: Chr.4:70656234 on build GRCh38
• Cytoband: 4q13.3

Target Gene Details

• Entrez Gene ID: 3512
• Gene Name: joining chain of multimeric IgA and IgM
• Gene Aliases: IGCJ, IGJ, JCH
• Location: Chr.4:70655541-70676901 on Build GRCh38
• Assay Gene Location: Within Exon 8

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
JCHAIN	NM_144646.3	4	716	NP_653247.1
	XM_006714211.2	5	681	XP_006714274.1
	XM_006714212.2	5	618	XP_006714275.1
	XM_011531925.1	5	618	XP_011530227.1
	XM_011531926.1	5	618	XP_011530228.1
	BC038982.1	4	632	AAH38982.1
	BX648421.1	1	2176

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv829965	Chr.4:70630001 - 70806591 on Build GRCh38	Gain	JCHAIN ENAM RUFY3 UTP3
nsv1012495	Chr.4:69979953 - 70947088 on Build GRCh38	Gain	PRR27 FDCSP CSN1S2AP MUC7 SMR3B ODAM CABS1 CSN1S2BP UTP3 HTN1 JCHAIN AMTN OPRPN SMR3A ENAM MOB1B GRSF1 CSN3 STATH HTN3 AMBN RUFY3

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

defense/immunity protein, immunoglobulin

Gene Ontology Categories:

Process(es)

retina homeostasis
adaptive immune response
glomerular filtration
receptor-mediated endocytosis
immune response
antibacterial humoral response
positive regulation of protein oligomerization
innate immune response
positive regulation of respiratory burst

Function(s)

single-stranded DNA binding
antigen binding
IgA binding
phosphatidylcholine binding
immunoglobulin receptor binding
protein homodimerization activity
peptidoglycan binding