Hs02826849_cn

• Gene Symbol: TBCD
• Assay Reference Genome Location: Chr.17:82829562 on build GRCh38
• Cytoband: 17q25.3

Target Gene Details

• Entrez Gene ID: 6904
• Gene Name: tubulin folding cofactor D
• Gene Aliases: SSD-1, tfcD
• Location: Chr.17:82752048-82943186 on Build GRCh38
• Assay Gene Location: Within Intron 18

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TBCD	NM_005993.4			NP_005984.3
	XM_005256396.4			XP_005256453.1
	XM_006722290.2			XP_006722353.1
	XM_011523589.1			XP_011521891.1
	XM_011523590.1			XP_011521892.1
	XM_011523591.1			XP_011521893.1
	XM_011523593.1			XP_011521895.1
	XM_017024987.1			XP_016880476.1
	XM_017024988.1			XP_016880477.1
	XM_017024990.1			XP_016880479.1
	AB023205.1
	AJ006417.1			CAA07022.1
	AK091959.1			BAC03777.1
	AK293471.1
	AL133562.1			CAB63716.1
	BC003094.1			AAH03094.1

Target Gene Details

• Entrez Gene ID: 79755
• Gene Name: zinc finger protein 750
• Gene Aliases: ZFP750
• Location: Chr.17:82829434-82840055 on Build GRCh38
• Assay Gene Location: Within Exon 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ZNF750	NM_024702.2	3	3063	NP_078978.2
	AI539029.1	1	156
	AK023903.1	3	3032	BAB14718.1
	BC109036.1	3	3022	AAI09037.1
	BC109037.1	3	3022	AAI09038.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1067553	Chr.17:82530808 - 83091923 on Build GRCh38	Loss	TBCD ZNF750 FN3KRP B3GNTL1 FOXK2 FN3K WDR45B MIR4525 LOC101929552 METRNL LOC105376791 LOC105371944 RAB40B
nsv833575	Chr.17:82660876 - 82847512 on Build GRCh38	Loss	MIR4525 TBCD LOC101929552 ZNF750 FN3KRP FN3K LOC105376791 RAB40B
nsv428351	Chr.17:81152631 - 83064073 on Build GRCh38	Gain	BAHCC1 TBCD FAAP100 ZNF750 ARL16 NPLOC4 LRRC45 GPS1 STRA13 MCRIP1 RFNG ACTG1 LOC101929552 GCGR HEXDC PDE6G UTS2R ASPSCR1 LINC00482 SLC25A10 TEPSIN ALYREF NPB TSPAN10 LOC100130370 NARF LOC105376790 TMEM105 CSNK1D PPP1R27 SLC38A10 LOC105371944 RAB40B CCDC57 MYADML2 MRPL12 ARHGDIA FN3KRP ANAPC11 CCDC137 FOXK2 NOTUM FN3K MIR6786 FSCN2 LOC101929511 HGS LOC105371925 MAFG-AS1 TEX19 OXLD1 MIR3186 C17orf89 DCXR C17orf62 P4HB MIR6787 MIR4740 CD7 MAFG RAC3 DUS1L AATK-AS1 SLC16A3 SIRT7 B3GNTL1 WDR45B CEP131 MIR4525 FASN SECTM1 OGFOD3 PCYT2 AATK SNORD134 LOC105376791 PYCR1
nsv1057589	Chr.17:82815790 - 82852057 on Build GRCh38	Loss	TBCD ZNF750
nsv833576	Chr.17:82769162 - 82847512 on Build GRCh38	Gain	TBCD ZNF750
esv2762577	Chr.17:82244836 - 82838431 on Build GRCh38	Gain+Loss	TBCD ZNF750 FN3KRP FOXK2 FN3K WDR45B LOC101929511 NARF MIR4525 LOC105376790 LOC101929552 TEX19 SECTM1 CSNK1D OGFOD3 C17orf62 HEXDC UTS2R LOC105376791 CD7 RAB40B
esv21913	Chr.17:81828123 - 83103548 on Build GRCh38	Gain+Loss	TBCD ZNF750 LRRC45 GPS1 STRA13 MCRIP1 RFNG LOC101929552 HEXDC UTS2R ASPSCR1 ALYREF NPB NARF LOC105376790 CSNK1D PPP1R27 LOC105371944 RAB40B CCDC57 MYADML2 ARHGDIA FN3KRP ANAPC11 FOXK2 NOTUM FN3K LOC101929511 MAFG-AS1 TEX19 METRNL DCXR C17orf62 P4HB MIR6787 CD7 MAFG RAC3 DUS1L SLC16A3 SIRT7 B3GNTL1 WDR45B MIR4525 FASN SECTM1 OGFOD3 PCYT2 SNORD134 LOC105376791 PYCR1

More Information

• Set Membership: Intragenic, Exonic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

chaperone

Gene Ontology Categories:

Process(es)

protein folding
tubulin complex assembly
post-chaperonin tubulin folding pathway
negative regulation of cell-substrate adhesion
negative regulation of microtubule polymerization
adherens junction assembly
positive regulation of GTPase activity
bicellular tight junction assembly
transcription from RNA polymerase II promoter
epidermis development
cell differentiation
positive regulation of transcription from RNA polymerase II promoter

Function(s)

GTPase activator activity
protein binding
beta-tubulin binding
chaperone binding
core promoter sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
metal ion binding