Hs02872637_cn

• Gene Symbol: CDH15
• Assay Reference Genome Location: Chr.16:89192316 on build GRCh38
• Cytoband: 16q24.3

Target Gene Details

• Entrez Gene ID: 1013
• Gene Name: cadherin 15
• Gene Aliases: CDH14, CDH3, CDHM, MCAD, MRD3
• Location: Chr.16:89171755-89195492 on Build GRCh38
• Assay Gene Location: Within Exon 11

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CDH15	NM_004933.2	11	1804	NP_004924.1
	BC008951.2	11	1779	AAH08951.1
	D83542.1	11	1804	BAA12012.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv509638	Chr.16:89152681 - 89296203 on Build GRCh38	Insertion	ANKRD11 ZNF778 LINC00304 ACSF3 LOC105371414 CDH15 LOC400558 SLC22A31
nsv952072	Chr.16:89032193 - 89201992 on Build GRCh38	Deletion	LINC00304 ACSF3 CDH15 LOC400558 SLC22A31
nsv573727	Chr.16:89169527 - 89193067 on Build GRCh38	Loss	CDH15
nsv1063024	Chr.16:88707330 - 89238482 on Build GRCh38	Gain	LOC105371409 LOC339059 CTU2 LOC100289580 LOC100129697 CDH15 LOC107987238 LOC400558 CBFA2T3 ZNF778 LINC00304 LOC101927793 MIR4722 PABPN1L GALNS ACSF3 APRT TRAPPC2L CDT1 PIEZO1 SLC22A31
nsv471115	Chr.16:88801844 - 89197442 on Build GRCh38	Loss	LOC105371409 LOC100129697 CDH15 LOC107987238 LOC400558 CBFA2T3 LINC00304 LOC101927793 PABPN1L GALNS ACSF3 APRT TRAPPC2L CDT1 SLC22A31
nsv573724	Chr.16:89100686 - 89217401 on Build GRCh38	Loss	ZNF778 LINC00304 ACSF3 CDH15 LOC400558 SLC22A31
nsv573674	Chr.16:88738775 - 89325907 on Build GRCh38	Gain	LOC105371409 LOC339059 ANKRD11 LOC100287036 LOC100289580 LOC100129697 CDH15 LOC107987238 LOC400558 CBFA2T3 ZNF778 LINC00304 LOC101927793 PABPN1L GALNS ACSF3 APRT TRAPPC2L LOC105371414 CDT1 PIEZO1 SLC22A31
nsv573729	Chr.16:89189723 - 89193067 on Build GRCh38	Loss	CDH15
dgv3066n100	Chr.16:89067685 - 89301626 on Build GRCh38	Gain	ANKRD11 ZNF778 LINC00304 ACSF3 LOC105371414 CDH15 LOC400558 SLC22A31
nsv482951	Chr.16:88633593 - 90228345 on Build GRCh38	Loss	GAS8 ZNF276 VPS9D1-AS1 CDH15 RNF166 LOC400558 VPS9D1 DBNDD1 GALNS AFG3L1P DPEP1 RPL13 ANKRD11 LOC100287036 CYBA LOC100289580 LOC100129697 TUBB8P7 FAM157C SNORD68 ZNF778 LINC00304 SNAI3-AS1 TUBB3 FANCA ACSF3 TRAPPC2L LOC105371414 CHMP1A CDK10 LOC107984817 PIEZO1 SPATA2L LOC339059 LOC105371419 URAHP CPNE7 SPATA33 CBFA2T3 LOC101927817 IL17C LOC101927793 MC1R MIR4722 PABPN1L APRT MVD CDT1 SNAI3 LOC105371409 CENPBD1 CTU2 TCF25 SPG7 LOC107987238 SPIRE2 DEF8 PRDM7 SLC22A31 GAS8-AS1
esv2763149	Chr.16:89179547 - 89368114 on Build GRCh38	Gain	ANKRD11 LOC100287036 ZNF778 LOC105371414 CDH15 SLC22A31
dgv5320n54	Chr.16:89114475 - 89197443 on Build GRCh38	Loss	LINC00304 ACSF3 CDH15 LOC400558 SLC22A31

More Information

Additional Information:

For this assay, SNP(s) [rs75791347] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

cadherin

Gene Ontology Categories:

Process(es)

cell adhesion
homophilic cell adhesion via plasma membrane adhesion molecules
adherens junction organization
positive regulation of muscle cell differentiation

Function(s)

calcium ion binding
protein binding