Hs02898840_cn

• Gene Symbol: PRH1
• Assay Reference Genome Location: Chr.12:11022320 on build GRCh38
• Cytoband: 12p13.2

Target Gene Details

• Entrez Gene ID: 5554
• Gene Name: proline rich protein HaeIII subfamily 1
• Gene Aliases: Db-s, PA, PIF-S, PRH2, Pr1/Pr2
• Location: Chr.12:10880961-11171623 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PRH1	NM_001291314.1			NP_001278243.1
	NM_001291315.1			NP_001278244.1
	NR_133575.1
	AB593028.1
	AB593029.1
	BI772091.1
	BM476484.1
	BU543118.1

Target Gene Details

• Entrez Gene ID: 100533464
• Gene Name: PRH1-PRR4 readthrough
• Gene Aliases: PRH1
• Location: Chr.12:10845849-11171625 on Build GRCh38
• Assay Gene Location: Within Intron 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PRH1-PRR4	NR_037918.2
	AB593030.1

Target Gene Details

• Entrez Gene ID: 259294
• Gene Name: taste 2 receptor member 19
• Gene Aliases: MSTP058, T2R19, T2R23, T2R48, TAS2R23, TAS2R48
• Location: Chr.12:11021619-11022620 on Build GRCh38
• Assay Gene Location: Within Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TAS2R19	NM_176888.2	1	301	NP_795369.1
	BC101804.1	1	301	AAI01805.1
	BC111998.1	1	313	AAI11999.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv514646	Chr.12:11021632 - 11022622 on Build GRCh38	Gain+Loss	PRH1-TAS2R14 TAS2R19 PRH1-PRR4 PRH1
nsv973027	Chr.12:11021169 - 11032136 on Build GRCh38	Duplication	PRH1-TAS2R14 TAS2R19 TAS2R31 PRH1-PRR4 PRH1
nsv1038709	Chr.12:11012518 - 11131235 on Build GRCh38	Loss	TAS2R46 PRH1-TAS2R14 TAS2R19 TAS2R31 PRH1-PRR4 PRH1 TAS2R43
esv3628556	Chr.12:10995613 - 11052888 on Build GRCh38	Loss	PRH1-TAS2R14 TAS2R19 TAS2R31 PRH1-PRR4 PRH1 TAS2R20
esv24685	Chr.12:11017964 - 11039747 on Build GRCh38	Loss	PRH1-TAS2R14 TAS2R19 TAS2R31 PRH1-PRR4 PRH1
nsv1070510	Chr.12:11015336 - 11070488 on Build GRCh38	Deletion	TAS2R46 PRH1-TAS2R14 TAS2R19 TAS2R31 PRH1-PRR4 PRH1
nsv1152044	Chr.12:11015335 - 11070462 on Build GRCh38	Deletion	TAS2R46 PRH1-TAS2R14 TAS2R19 TAS2R31 PRH1-PRR4 PRH1
dgv172e201	Chr.12:11020588 - 11137077 on Build GRCh38	Deletion	TAS2R30 TAS2R46 PRH1-TAS2R14 TAS2R19 TAS2R31 PRH1-PRR4 PRH1 TAS2R43
esv8289	Chr.12:10991798 - 11069760 on Build GRCh38	Loss	TAS2R46 PRH1-TAS2R14 TAS2R19 TAS2R31 PRH1-PRR4 PRH1 TAS2R20
dgv265e199	Chr.12:11014581 - 11075113 on Build GRCh38	Deletion	TAS2R46 PRH1-TAS2R14 TAS2R19 TAS2R31 PRH1-PRR4 PRH1
nsv8917	Chr.12:11015633 - 11141148 on Build GRCh38	Loss	TAS2R30 TAS2R46 PRH1-TAS2R14 TAS2R19 TAS2R31 PRH1-PRR4 PRH1 TAS2R43
esv2664609	Chr.12:10995640 - 11052917 on Build GRCh38	Deletion	PRH1-TAS2R14 TAS2R19 TAS2R31 PRH1-PRR4 PRH1 TAS2R20
dgv769n106	Chr.12:11015331 - 11070457 on Build GRCh38	Deletion	TAS2R46 PRH1-TAS2R14 TAS2R19 TAS2R31 PRH1-PRR4 PRH1
esv2760999	Chr.12:11018238 - 11123437 on Build GRCh38	Gain+Loss	TAS2R46 PRH1-TAS2R14 TAS2R19 TAS2R31 PRH1-PRR4 PRH1 TAS2R43
dgv42e19	Chr.12:11013959 - 11075814 on Build GRCh38	Loss	TAS2R46 PRH1-TAS2R14 TAS2R19 TAS2R31 PRH1-PRR4 PRH1
dgv266e199	Chr.12:11021769 - 11049166 on Build GRCh38	Deletion	PRH1-TAS2R14 TAS2R19 TAS2R31 PRH1-PRR4 PRH1
esv2670207	Chr.12:11008725 - 11123187 on Build GRCh38	Deletion	TAS2R46 PRH1-TAS2R14 TAS2R19 TAS2R31 PRH1-PRR4 PRH1 TAS2R43
nsv832330	Chr.12:10925079 - 11054358 on Build GRCh38	Gain	PRH1-TAS2R14 TAS2R19 TAS2R31 PRH2 TAS2R14 TAS2R50 PRH1-PRR4 PRH1 TAS2R20
esv2759879	Chr.12:10817021 - 11561987 on Build GRCh38	Loss	TAS2R30 PRB4 TAS2R46 PRH1-TAS2R14 TAS2R14 TAS2R13 TAS2R50 PRH1-PRR4 PRH1 TAS2R42 PRB1 PRB3 TAS2R20 PRR4 LINC01252 PRB2 TAS2R19 TAS2R31 PRH2 SMIM10L1 TAS2R43 TAS2R10
nsv1038277	Chr.12:10908379 - 11351157 on Build GRCh38	Loss	TAS2R30 PRB4 TAS2R46 PRH1-TAS2R14 TAS2R14 TAS2R13 TAS2R50 PRH1-PRR4 PRH1 TAS2R42 PRB3 TAS2R20 TAS2R19 TAS2R31 PRH2 SMIM10L1 TAS2R43
esv2745546	Chr.12:10980833 - 11078852 on Build GRCh38	Deletion	TAS2R46 PRH1-TAS2R14 TAS2R19 TAS2R31 TAS2R50 PRH1-PRR4 PRH1 TAS2R20
nsv428272	Chr.12:10917246 - 11561987 on Build GRCh38	Gain+Loss	TAS2R30 PRB4 TAS2R46 PRH1-TAS2R14 TAS2R14 TAS2R50 PRH1-PRR4 PRH1 TAS2R42 PRB1 PRB3 TAS2R20 LINC01252 PRB2 TAS2R19 TAS2R31 PRH2 SMIM10L1 TAS2R43

More Information

• Set Membership: Intragenic, Exonic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

antimicrobial response protein, transmembrane signal receptor

Gene Ontology Categories:

Process(es)

detection of chemical stimulus involved in sensory perception of bitter taste
G-protein coupled receptor signaling pathway

Function(s)

protein binding
G-protein coupled receptor activity
bitter taste receptor activity