Hs02924401_cn

• Gene Symbol: TBCD
• Assay Reference Genome Location: Chr.17:82830498 on build GRCh38
• Cytoband: 17q25.3

Target Gene Details

• Entrez Gene ID: 6904
• Gene Name: tubulin folding cofactor D
• Gene Aliases: SSD-1, tfcD
• Location: Chr.17:82752048-82943186 on Build GRCh38
• Assay Gene Location: Within Intron 18

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TBCD	NM_005993.4			NP_005984.3
	XM_005256396.4			XP_005256453.1
	XM_006722290.2			XP_006722353.1
	XM_011523589.1			XP_011521891.1
	XM_011523590.1			XP_011521892.1
	XM_011523591.1			XP_011521893.1
	XM_011523593.1			XP_011521895.1
	XM_017024987.1			XP_016880476.1
	XM_017024988.1			XP_016880477.1
	XM_017024990.1			XP_016880479.1
	AB023205.1
	AJ006417.1			CAA07022.1
	AK091959.1			BAC03777.1
	AK293471.1
	AL133562.1			CAB63716.1
	BC003094.1			AAH03094.1

Target Gene Details

• Entrez Gene ID: 79755
• Gene Name: zinc finger protein 750
• Gene Aliases: ZFP750
• Location: Chr.17:82829434-82840055 on Build GRCh38
• Assay Gene Location: Within Exon 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ZNF750	NM_024702.2	3	2127	NP_078978.2
	AK023903.1	3	2096	BAB14718.1
	AK301690.1	4	903
	BC109036.1	3	2086	AAI09037.1
	BC109037.1	3	2086	AAI09038.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1067553	Chr.17:82530808 - 83091923 on Build GRCh38	Loss	B3GNTL1 WDR45B LOC105376791 METRNL FOXK2 RAB40B MIR4525 LOC101929552 ZNF750 TBCD FN3KRP FN3K LOC105371944
nsv833575	Chr.17:82660876 - 82847512 on Build GRCh38	Loss	MIR4525 LOC101929552 ZNF750 LOC105376791 TBCD FN3KRP FN3K RAB40B
nsv428351	Chr.17:81152631 - 83064073 on Build GRCh38	Gain	BAHCC1 CEP131 FOXK2 TEPSIN GPS1 CCDC137 PDE6G FSCN2 FAAP100 MRPL12 SNORD134 MIR3186 C17orf62 PCYT2 RFNG NOTUM STRA13 MYADML2 FN3K RAC3 B3GNTL1 LOC105371925 OXLD1 OGFOD3 MIR6787 SIRT7 UTS2R ARHGDIA LOC101929511 AATK MIR4740 MAFG-AS1 FASN LOC100130370 NPB SLC38A10 FN3KRP ALYREF DCXR HEXDC SECTM1 DUS1L MCRIP1 WDR45B NARF LOC105376791 CCDC57 TMEM105 PPP1R27 ASPSCR1 MIR6786 CD7 TSPAN10 SLC25A10 ZNF750 P4HB CSNK1D AATK-AS1 TBCD LOC105371944 LOC105376790 ANAPC11 HGS MAFG PYCR1 SLC16A3 GCGR TEX19 LRRC45 LINC00482 RAB40B ACTG1 NPLOC4 MIR4525 LOC101929552 C17orf89 ARL16
nsv1057589	Chr.17:82815790 - 82852057 on Build GRCh38	Loss	ZNF750 TBCD
nsv833576	Chr.17:82769162 - 82847512 on Build GRCh38	Gain	ZNF750 TBCD
esv2762577	Chr.17:82244836 - 82838431 on Build GRCh38	Gain+Loss	HEXDC SECTM1 OGFOD3 WDR45B NARF LOC105376791 FOXK2 UTS2R TEX19 LOC101929511 RAB40B MIR4525 CD7 C17orf62 LOC101929552 ZNF750 CSNK1D TBCD FN3KRP FN3K LOC105376790
esv21913	Chr.17:81828123 - 83103548 on Build GRCh38	Gain+Loss	METRNL FOXK2 GPS1 SNORD134 C17orf62 PCYT2 RFNG NOTUM STRA13 MYADML2 FN3K RAC3 B3GNTL1 OGFOD3 MIR6787 SIRT7 UTS2R ARHGDIA LOC101929511 MAFG-AS1 FASN NPB FN3KRP ALYREF DCXR HEXDC SECTM1 DUS1L MCRIP1 WDR45B NARF LOC105376791 CCDC57 PPP1R27 ASPSCR1 CD7 ZNF750 P4HB CSNK1D TBCD LOC105371944 LOC105376790 ANAPC11 MAFG PYCR1 SLC16A3 TEX19 LRRC45 RAB40B MIR4525 LOC101929552

More Information

• Set Membership: Intragenic, Exonic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

chaperone

Gene Ontology Categories:

Process(es)

protein folding
tubulin complex assembly
post-chaperonin tubulin folding pathway
negative regulation of cell-substrate adhesion
negative regulation of microtubule polymerization
adherens junction assembly
positive regulation of GTPase activity
bicellular tight junction assembly
transcription from RNA polymerase II promoter
epidermis development
cell differentiation
positive regulation of transcription from RNA polymerase II promoter

Function(s)

GTPase activator activity
protein binding
beta-tubulin binding
chaperone binding
core promoter sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
metal ion binding