Hs02945137_cn

• Gene Symbol: AMER3
• Assay Reference Genome Location: Chr.2:130764290 on build GRCh38
• Cytoband: 2q21.1

Target Gene Details

• Entrez Gene ID: 205147
• Gene Name: APC membrane recruitment protein 3
• Gene Aliases: FAM123C
• Location: Chr.2:130754475-130768134 on Build GRCh38
• Assay Gene Location: Within Exon 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
AMER3	NM_001105193.1	2	2392	NP_001098663.1
	NM_001105194.1	2	2328	NP_001098664.1
	NM_001105195.1	2	2325	NP_001098665.1
	NM_152698.2	2	2408	NP_689911.2
	XM_011510793.2	2	3434	XP_011509095.1
	AK095696.1	2	2372	BAC04612.1
	AK289525.1	2	2477
	AK291424.1	2	2372
	BC113445.1	2	2285
	BC113447.1	2	2285
	BC143806.1	2	2282

Target Gene Details

• Entrez Gene ID: 653269
• Gene Name: POTE ankyrin domain family member I
• Gene Aliases: POTE2beta
• Location: Chr.2:130462245-131626428 on Build GRCh38
• Assay Gene Location:

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
POTEI

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv4074n100	Chr.2:130550793 - 131291209 on Build GRCh38	Gain	LOC440910 POTEE TISP43 POTEI ARHGEF4 AMER3 FAM168B CFC1 PLEKHB2 GPR148 CYP4F30P POTEJ
dgv731e199	Chr.2:130678437 - 131300107 on Build GRCh38	Deletion	LOC440910 POTEE POTEI ARHGEF4 AMER3 FAM168B PLEKHB2 GPR148 CYP4F30P
esv2670824	Chr.2:130625264 - 131605218 on Build GRCh38	Deletion	LOC440910 MZT2A POTEE POTEKP POTEI TUBA3D AMER3 LOC150776 NOC2LP2 CYP4F30P WTH3DI ARHGEF4 CCDC74A LINC01120 MIR4784 FAM168B PLEKHB2 GPR148 POTEJ
nsv583136	Chr.2:130730100 - 130846832 on Build GRCh38	Loss	POTEI ARHGEF4 AMER3 GPR148
dgv4075n100	Chr.2:130720375 - 131521740 on Build GRCh38	Gain	LOC440910 MZT2A POTEE POTEI TUBA3D AMER3 LOC150776 NOC2LP2 WTH3DI ARHGEF4 LINC01120 MIR4784 FAM168B PLEKHB2 GPR148
esv3893337	Chr.2:130722838 - 131194387 on Build GRCh38	Loss	POTEI ARHGEF4 AMER3 FAM168B PLEKHB2 GPR148
dgv616e201	Chr.2:130674635 - 131312550 on Build GRCh38	Deletion	LOC440910 POTEE POTEI ARHGEF4 AMER3 FAM168B PLEKHB2 GPR148 CYP4F30P
nsv583135	Chr.2:130724905 - 131194388 on Build GRCh38	Loss	POTEI ARHGEF4 AMER3 FAM168B PLEKHB2 GPR148
nsv524021	Chr.2:130724906 - 131553515 on Build GRCh38	Loss	LOC440910 MZT2A POTEE POTEI TUBA3D AMER3 LOC150776 NOC2LP2 WTH3DI ARHGEF4 CCDC74A LINC01120 MIR4784 FAM168B PLEKHB2 GPR148
nsv10175	Chr.2:130762563 - 130766308 on Build GRCh38	Loss	POTEI AMER3
esv2760576	Chr.2:130634172 - 131521752 on Build GRCh38	Gain+Loss	LOC440910 MZT2A POTEE POTEI TUBA3D AMER3 LOC150776 NOC2LP2 CYP4F30P WTH3DI ARHGEF4 LINC01120 MIR4784 FAM168B PLEKHB2 GPR148 POTEJ
esv2759092	Chr.2:129589265 - 132440430 on Build GRCh38	Gain+Loss	TISP43 LOC100507460 RAB6C CYP4F30P WTH3DI LINC01087 ARHGEF4 MIR4784 FAR2P2 FAR2P1 GPR148 LOC389033 MZT2A CYP4F62P ANKRD30BL TUBA3D AMER3 RAB6C-AS1 IMP4 C2orf27B PTPN18 LOC107985778 C2orf27A LOC646743 TUBA3E FAM168B SMPD4 PLEKHB2 POTEJ POTEE CFC1 MIR663B FAM201B CCDC74B MZT2B LOC440910 CCDC115 POTEKP LOC101927924 POTEI LOC150776 NOC2LP2 POTEF CCDC74A LINC01120 GPR39 NOC2LP1 CFC1B ZNF806 MED15P9
nsv428403	Chr.2:129818076 - 130882067 on Build GRCh38	Loss	TISP43 CFC1 RAB6C CYP4F30P ARHGEF4 FAR2P2 CCDC74B FAR2P1 GPR148 LOC389033 MZT2B CCDC115 LOC101927924 CYP4F62P POTEI AMER3 RAB6C-AS1 IMP4 PTPN18 LOC107985778 LOC646743 POTEF TUBA3E SMPD4 NOC2LP1 CFC1B POTEJ MED15P9

More Information

• Set Membership: Intragenic, Exonic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

Wnt signaling pathway
anatomical structure development
regulation of canonical Wnt signaling pathway

Function(s)

protein binding
phosphatidylinositol-4,5-bisphosphate binding
beta-catenin binding