Hs03017352_cn

• Gene Symbol: ARHGAP11A
• Assay Reference Genome Location: Chr.15:32638490 on build GRCh38
• Cytoband: 15q13.3

Target Gene Details

• Entrez Gene ID: 9824
• Gene Name: Rho GTPase activating protein 11A
• Gene Aliases: GAP (1-12)
• Location: Chr.15:32615144-32639949 on Build GRCh38
• Assay Gene Location: Within Exon 13

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ARHGAP11A	NM_001286479.1	12	3698	NP_001273408.1
	NM_001286480.1	13	3820	NP_001273409.1
	NM_014783.4	12	4439	NP_055598.1
	D87717.2	12	4439

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv517740	Chr.15:31727863 - 32666510 on Build GRCh38	Gain+Loss	LOC101928042 LOC101060588 GOLGA8K LOC105370940 LOC105370757 GOLGA8N ULK4P1 GOLGA8O WHAMMP1 CHRNA7 LOC100996255 LOC100653133 SCG5 ARHGAP11A
nsv456785	Chr.15:32633875 - 33060788 on Build GRCh38	Gain	FMN1 GREM1 LOC105370757 SCG5 ARHGAP11A LOC100131315
nsv1481	Chr.15:32635939 - 32642395 on Build GRCh38	Deletion	SCG5 ARHGAP11A
nsv428302	Chr.15:31646275 - 32694378 on Build GRCh38	Gain+Loss	LOC101928042 LOC101060588 GOLGA8K LOC105370940 LOC105370757 GOLGA8N ULK4P1 GOLGA8O OTUD7A WHAMMP1 CHRNA7 LOC100996255 LOC100653133 SCG5 ARHGAP11A
esv2760023	Chr.15:31474097 - 32694378 on Build GRCh38	Gain+Loss	LOC101928042 LOC101060588 GOLGA8K LOC105370940 LOC105370757 GOLGA8N ULK4P1 GOLGA8O OTUD7A WHAMMP1 CHRNA7 LOC100996255 LOC100653133 SCG5 ARHGAP11A
nsv1052620	Chr.15:32612402 - 34538731 on Build GRCh38	Gain	LOC101928042 NOP10 SLC12A6 LOC105370757 MIR1233-2 LOC101928134 EMC4 CHRM5 GOLGA8A MIR1233-1 NUTM1 RYR3 TMCO5B FMN1 LPCAT4 GREM1 GOLGA8B EMC7 SCG5 KATNBL1 ARHGAP11A PGBD4 LOC100131315 AVEN
nsv483039	Chr.15:32574635 - 32751321 on Build GRCh38	Gain	LOC101928042 LOC100996255 GREM1 LOC105370757 GOLGA8N SCG5 ARHGAP11A LOC100131315
esv3892661	Chr.15:32393132 - 32776080 on Build GRCh38	Gain	LOC101928042 LOC101060588 GOLGA8K LOC105370757 GOLGA8N ULK4P1 GOLGA8O WHAMMP1 LOC100996255 LOC100653133 FMN1 GREM1 SCG5 ARHGAP11A LOC100131315
esv33337	Chr.15:31689863 - 34575097 on Build GRCh38	Gain+Loss	LOC101060588 GOLGA8K LOC105370940 LOC105370757 LOC101928134 GOLGA8N ULK4P1 GOLGA8O GOLGA8A LOC100996255 LOC100653133 MIR1233-1 NUTM1 RYR3 LPCAT4 GREM1 SCG5 KATNBL1 LOC100131315 LOC101928042 NOP10 SLC12A6 MIR1233-2 EMC4 WHAMMP1 CHRNA7 CHRM5 TMCO5B FMN1 GOLGA8B EMC7 ARHGAP11A PGBD4 AVEN
nsv469587	Chr.15:32529739 - 32694378 on Build GRCh38	Loss	LOC101928042 LOC100996255 LOC105370757 GOLGA8N SCG5 WHAMMP1 ARHGAP11A
esv2422296	Chr.15:32506737 - 32929014 on Build GRCh38	Duplication	LOC101928042 LOC100996255 FMN1 GREM1 LOC105370757 GOLGA8N SCG5 WHAMMP1 ARHGAP11A LOC100131315
dgv4456n54	Chr.15:32604149 - 34557061 on Build GRCh38	Gain	LOC105370757 LOC101928134 GOLGA8N GOLGA8A MIR1233-1 NUTM1 RYR3 LPCAT4 GREM1 SCG5 KATNBL1 LOC100131315 LOC101928042 NOP10 SLC12A6 MIR1233-2 EMC4 CHRM5 TMCO5B FMN1 GOLGA8B EMC7 ARHGAP11A PGBD4 AVEN

More Information

Additional Information:

For this assay, SNP(s) [rs117552784] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

G-protein modulator, protein-binding activity modulator, GTPase-activating protein

Gene Ontology Categories:

Process(es)

signal transduction
positive regulation of GTPase activity
regulation of small GTPase mediated signal transduction

Function(s)

GTPase activator activity