Hs03020122_cn

• Gene Symbol: ANAPC2
• Assay Reference Genome Location: Chr.9:137175135 on build GRCh38
• Cytoband: 9q34.3

Target Gene Details

• Entrez Gene ID: 29882
• Gene Name: anaphase promoting complex subunit 2
• Gene Aliases: APC2
• Location: Chr.9:137174784-137188605 on Build GRCh38
• Assay Gene Location: Overlaps Intron 12 - Exon 13

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ANAPC2	NM_013366.3			NP_037498.1
	AB037827.1			BAA92644.1
	AF191337.1			AAF05751.1
	AK294601.1
	BC001579.1			AAH01579.1
	BC009487.2			AAH09487.2
	BC032503.1			AAH32503.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv616007	Chr.9:137079368 - 137240666 on Build GRCh38	Loss	SSNA1 GRIN1 UAP1L1 LRRC26 SLC34A3 MAN1B1-AS1 TMEM210 ANAPC2 RNF208 CYSRT1 TMEM203 LOC101930307 DPP7 NDOR1 MAN1B1 RNF224 MIR3621 TPRN
dgv13009n54	Chr.9:137173890 - 137327859 on Build GRCh38	Loss	SSNA1 SLC34A3 NRARP ANAPC2 RNF208 CYSRT1 FAM166A TMEM203 NDOR1 EXD3 RNF224 TOR4A STPG3 TUBB4B NELFB TPRN C9orf173-AS1
nsv524322	Chr.9:136795692 - 137482216 on Build GRCh38	Loss	UAP1L1 LRRC26 SLC34A3 NRARP TMEM210 MAMDC4 PTGDS ANAPC2 CCDC183 C9orf139 CYSRT1 EXD3 TOR4A C8G TPRN PHPT1 MAN1B1-AS1 NOXA1 RNF208 FAM166A CLIC3 LOC101930307 DPP7 NDOR1 MIR7114 STPG3 NSMF TUBB4B MIR3621 NELFB PNPLA7 RABL6 C9orf173-AS1 SSNA1 GRIN1 CCDC183-AS1 MIR4292 ENTPD8 MIR4479 ENTPD2 FUT7 SAPCD2 RNF224 LCNL1 TRAF2 ABCA2 EDF1 C9orf172 FBXW5 C9orf142 NPDC1 LCN12 TMEM203 MAN1B1 PRR31
nsv951207	Chr.9:137136949 - 137379148 on Build GRCh38	Deletion	SSNA1 GRIN1 LRRC26 SLC34A3 NRARP TMEM210 ANAPC2 RNF208 CYSRT1 FAM166A TMEM203 NDOR1 EXD3 RNF224 TOR4A STPG3 TUBB4B MIR3621 NELFB TPRN C9orf173-AS1
nsv1161918	Chr.9:137118319 - 137438026 on Build GRCh38	Duplication	SSNA1 GRIN1 LRRC26 SLC34A3 NRARP NOXA1 TMEM210 ENTPD8 ANAPC2 RNF208 CYSRT1 FAM166A TMEM203 NDOR1 EXD3 RNF224 TOR4A STPG3 TUBB4B MIR3621 NELFB TPRN C9orf173-AS1
esv2761561	Chr.9:137030185 - 137191593 on Build GRCh38	Gain	SSNA1 GRIN1 UAP1L1 LRRC26 MAN1B1-AS1 TMEM210 ANAPC2 C9orf139 NPDC1 ENTPD2 FUT7 LOC101930307 DPP7 MAN1B1 SAPCD2 MIR3621
esv2422220	Chr.9:136584135 - 137350098 on Build GRCh38	Deletion	FAM69B AGPAT2 UAP1L1 LRRC26 SLC34A3 NRARP LCN6 TMEM210 MAMDC4 PTGDS ANAPC2 CCDC183 C9orf139 CYSRT1 EXD3 TOR4A LCN8 C8G LOC100128593 TPRN PHPT1 MAN1B1-AS1 HSPC324 SNORA17B RNF208 FAM166A CLIC3 LOC101930307 DPP7 NDOR1 STPG3 TUBB4B MIR3621 LINC01451 NELFB RABL6 C9orf173-AS1 SSNA1 GRIN1 CCDC183-AS1 MIR6722 MIR4292 LCN15 MIR4479 MIR126 EGFL7 ENTPD2 FUT7 SAPCD2 SNORA17A RNF224 TMEM141 LCNL1 TRAF2 ABCA2 EDF1 SNHG7 C9orf172 FBXW5 C9orf142 NPDC1 LCN12 TMEM203 MAN1B1 PRR31 LCN10

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

mitotic nuclear division
anaphase-promoting complex-dependent catabolic process
positive regulation of synaptic plasticity
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
proteasome-mediated ubiquitin-dependent protein catabolic process
positive regulation of axon extension
positive regulation of dendrite morphogenesis
cell division
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
protein K11-linked ubiquitination
positive regulation of synapse maturation

Function(s)

ubiquitin protein ligase binding
ubiquitin protein ligase activity