Hs03034949_cn

• Gene Symbol: CYP1A1
• Assay Reference Genome Location: Chr.15:74723070 on build GRCh38
• Cytoband: 15q24.1

Target Gene Details

• Entrez Gene ID: 1543
• Gene Name: cytochrome P450 family 1 subfamily A member 1
• Gene Aliases: AHH, AHRR, CP11, CYP1, CYPIA1, P1-450, P450-C, P450DX
• Location: Chr.15:74719542-74725610 on Build GRCh38
• Assay Gene Location: Within Exon 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CYP1A1	NM_000499.4	2	224	NP_000490.1
	NM_001319216.1	2	227	NP_001306145.1
	NM_001319217.1	2	227	NP_001306146.1
	XM_017021953.1	2	227	XP_016877442.1
	AK223108.1	2	145	BAD96828.1
	AK223113.1	2	142	BAD96833.1
	AK310810.1	2	271
	AK313880.1	2	142
	AM233517.1
	AM233518.1
	AM233519.1	2	105
	AM233520.1	2	105
	AM236046.1	2	105
	AM236047.1
	AY310359.1			AAQ76692.1
	AY871801.1	2	111
	BC023019.1	2	109	AAH23019.1
	DA693879.1	2	227
	K03191.1	2	114	AAA52139.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv833055	Chr.15:74696003 - 74873947 on Build GRCh38	Loss	ULK3 MIR4513 LMAN1L MIR6882 CPLX3 EDC3 CYP1A1 CYP1A2 CSK SCAMP2
esv3636907	Chr.15:74721538 - 74745196 on Build GRCh38	Loss	CYP1A1
nsv817698	Chr.15:74596822 - 74727108 on Build GRCh38	Gain	LOC102723750 CLK3 ARID3B EDC3 CYP1A1
esv2763106	Chr.15:74722123 - 74741845 on Build GRCh38	Loss	CYP1A1
nsv1121512	Chr.15:72670085 - 75273877 on Build GRCh38	Deletion	LOC732265 C15orf59 MIR4513 RPP25 LOC107984728 LOXL1-AS1 ADPGK NEO1 FAM219B ISLR MPI ADPGK-AS1 GOLGA6C EDC3 SEMA7A CSK MIR6881 UBL7 LOC729739 HIGD2B LOC283731 UBL7-AS1 CLK3 COX5A C15orf39 PML ULK3 CCDC33 PPCDC NPTN-IT1 STRA6 SCAMP5 HCN4 LOC101929333 C15orf59-AS1 NPTN CYP1A1 STOML1 CYP1A2 MIR6882 LOXL1 CD276 ARID3B LOC105376731 BBS4 CYP11A1 LOC102723750 TBC1D21 REC114 LMAN1L ISLR2 CPLX3 GOLGA6A SCAMP2

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

response to hypoxia
porphyrin-containing compound metabolic process
aging
cell proliferation
amine metabolic process
response to wounding
response to virus
response to nematode
response to herbicide
ethylene metabolic process
embryo development ending in birth or egg hatching
coumarin metabolic process
flavonoid metabolic process
response to iron(III) ion
insecticide metabolic process
drug metabolic process
dibenzo-p-dioxin catabolic process
epoxygenase P450 pathway
response to food
response to lipopolysaccharide
response to vitamin A
response to immobilization stress
vitamin D metabolic process
response to drug
9-cis-retinoic acid biosynthetic process
camera-type eye development
response to antibiotic
response to arsenic-containing substance
digestive tract development
hydrogen peroxide biosynthetic process
response to hyperoxia
oxidation-reduction process
maternal process involved in parturition
hepatocyte differentiation
demethylation
cellular response to organic cyclic compound
omega-hydroxylase P450 pathway
positive regulation of G1/S transition of mitotic cell cycle

Function(s)

monooxygenase activity
iron ion binding
protein binding
steroid hydroxylase activity
oxidoreductase activity
oxidoreductase activity, acting on diphenols and related substances as donors
flavonoid 3'-monooxygenase activity
oxygen binding
enzyme binding
heme binding
demethylase activity
aromatase activity
vitamin D 24-hydroxylase activity