Hs03064483_cn

• Gene Symbol: ANAPC2
• Assay Reference Genome Location: Chr.9:137183158 on build GRCh38
• Cytoband: 9q34.3

Target Gene Details

• Entrez Gene ID: 29882
• Gene Name: anaphase promoting complex subunit 2
• Gene Aliases: APC2
• Location: Chr.9:137174784-137188605 on Build GRCh38
• Assay Gene Location: Within Exon 6

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ANAPC2	NM_013366.3	6	1326	NP_037498.1
	AB037827.1	4	502	BAA92644.1
	AF191337.1	6	1253	AAF05751.1
	AK294601.1	6	1281
	BC001579.1	4	518	AAH01579.1
	BC009487.2	2	117	AAH09487.2
	BC032503.1	6	1258	AAH32503.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv616007	Chr.9:137079368 - 137240666 on Build GRCh38	Loss	MIR3621 RNF224 LRRC26 RNF208 UAP1L1 MAN1B1-AS1 NDOR1 LOC101930307 TMEM203 ANAPC2 SSNA1 DPP7 SLC34A3 GRIN1 TPRN CYSRT1 MAN1B1 TMEM210
dgv13009n54	Chr.9:137173890 - 137327859 on Build GRCh38	Loss	RNF224 RNF208 NDOR1 STPG3 NELFB NRARP TMEM203 ANAPC2 FAM166A TUBB4B C9orf173-AS1 SSNA1 TOR4A SLC34A3 EXD3 TPRN CYSRT1
nsv524322	Chr.9:136795692 - 137482216 on Build GRCh38	Loss	C9orf172 MIR3621 C9orf142 LRRC26 UAP1L1 NDOR1 NOXA1 RABL6 NELFB LOC101930307 TMEM203 DPP7 SLC34A3 GRIN1 ENTPD8 TPRN ABCA2 CYSRT1 TMEM210 RNF224 C8G RNF208 STPG3 FUT7 NSMF FAM166A C9orf173-AS1 SSNA1 TOR4A CLIC3 ENTPD2 PNPLA7 LCNL1 NPDC1 LCN12 CCDC183-AS1 EDF1 CCDC183 MIR4479 NRARP ANAPC2 MAN1B1 TRAF2 PHPT1 MAN1B1-AS1 PRR31 MIR4292 MAMDC4 PTGDS C9orf139 TUBB4B FBXW5 SAPCD2 MIR7114 EXD3
nsv951207	Chr.9:137136949 - 137379148 on Build GRCh38	Deletion	MIR3621 RNF224 LRRC26 RNF208 NDOR1 STPG3 NELFB NRARP TMEM203 ANAPC2 FAM166A TUBB4B C9orf173-AS1 SSNA1 TOR4A SLC34A3 GRIN1 EXD3 TPRN CYSRT1 TMEM210
nsv1161918	Chr.9:137118319 - 137438026 on Build GRCh38	Duplication	MIR3621 RNF224 LRRC26 RNF208 NDOR1 STPG3 NOXA1 NELFB NRARP TMEM203 ANAPC2 FAM166A TUBB4B C9orf173-AS1 SSNA1 TOR4A SLC34A3 GRIN1 EXD3 ENTPD8 TPRN CYSRT1 TMEM210
esv2761561	Chr.9:137030185 - 137191593 on Build GRCh38	Gain	MIR3621 NPDC1 LRRC26 UAP1L1 MAN1B1-AS1 FUT7 C9orf139 LOC101930307 ANAPC2 SSNA1 SAPCD2 DPP7 ENTPD2 GRIN1 MAN1B1 TMEM210
esv2422220	Chr.9:136584135 - 137350098 on Build GRCh38	Deletion	C9orf172 MIR3621 TMEM141 C9orf142 LRRC26 UAP1L1 NDOR1 LCN15 RABL6 NELFB SNORA17B LOC101930307 TMEM203 LOC100128593 DPP7 SLC34A3 GRIN1 TPRN ABCA2 CYSRT1 TMEM210 RNF224 C8G RNF208 STPG3 FUT7 FAM166A C9orf173-AS1 SSNA1 SNHG7 AGPAT2 HSPC324 TOR4A CLIC3 ENTPD2 EGFL7 LCNL1 NPDC1 LCN12 CCDC183-AS1 LINC01451 EDF1 CCDC183 MIR4479 LCN8 NRARP MIR126 ANAPC2 MAN1B1 SNORA17A TRAF2 PHPT1 LCN10 MAN1B1-AS1 PRR31 MIR4292 MAMDC4 PTGDS C9orf139 TUBB4B FAM69B MIR6722 LCN6 FBXW5 SAPCD2 EXD3

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

mitotic nuclear division
anaphase-promoting complex-dependent catabolic process
positive regulation of synaptic plasticity
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
proteasome-mediated ubiquitin-dependent protein catabolic process
positive regulation of axon extension
positive regulation of dendrite morphogenesis
cell division
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
protein K11-linked ubiquitination
positive regulation of synapse maturation

Function(s)

ubiquitin protein ligase binding
ubiquitin protein ligase activity