Hs03066718_cn

• Gene Symbol: PPP2CA
• Assay Reference Genome Location: Chr.5:134196505 on build GRCh38
• Cytoband: 5q31.1

Target Gene Details

• Entrez Gene ID: 5515
• Gene Name: protein phosphatase 2 catalytic subunit alpha
• Gene Aliases: PP2Ac, PP2CA, PP2Calpha, RP-C
• Location: Chr.5:134196457-134226259 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 7

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PPP2CA	NM_002715.2			NP_002706.1
	AK097599.1
	BM786995.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv599732	Chr.5:134099223 - 134230401 on Build GRCh38	Loss	TCF7 PPP2CA SKP1 MIR3661

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

protein phosphatase

Gene Ontology Categories:

Process(es)

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
inactivation of MAPK activity
regulation of DNA replication
regulation of transcription, DNA-templated
protein dephosphorylation
ceramide metabolic process
apoptotic process
mitotic nuclear envelope reassembly
mesoderm development
RNA splicing
response to organic substance
negative regulation of epithelial to mesenchymal transition
second-messenger-mediated signaling
regulation of Wnt signaling pathway
regulation of cell adhesion
negative regulation of cell growth
regulation of growth
negative regulation of tyrosine phosphorylation of Stat3 protein
regulation of cell differentiation
meiotic cell cycle
positive regulation of protein serine/threonine kinase activity

Function(s)

phosphoprotein phosphatase activity
protein binding
protein C-terminus binding
metal ion binding
GABA receptor binding