Hs03068593_cn

• Gene Symbol: SLC18A1
• Assay Reference Genome Location: Chr.8:20174401 on build GRCh38
• Cytoband: 8p21.3

Target Gene Details

• Entrez Gene ID: 6570
• Gene Name: solute carrier family 18 member A1
• Gene Aliases: CGAT, VAT1, VMAT1
• Location: Chr.8:20144855-20183206 on Build GRCh38
• Assay Gene Location: Overlaps Intron 5 - Exon 6

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SLC18A1	NM_001135691.2			NP_001129163.1
	NM_001142324.1			NP_001135796.1
	NM_001142325.1			NP_001135797.1
	NM_003053.3			NP_003044.1
	XM_011544625.1			XP_011542927.1
	XM_011544626.1			XP_011542928.1
	XM_011544627.1			XP_011542929.1
	AK313720.1
	BC006317.2			AAH06317.1
	BC009387.2			AAH09387.1
	U39905.1			AAC50472.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv508498	Chr.8:20127378 - 20174629 on Build GRCh38	Deletion	SLC18A1
nsv610759	Chr.8:19704486 - 20211331 on Build GRCh38	Gain	CSGALNACT1 SLC18A1 ATP6V1B2 INTS10 LPL
nsv522185	Chr.8:19097292 - 20497802 on Build GRCh38	Gain	CSGALNACT1 SLC18A1 SH2D4A LZTS1 ATP6V1B2 LZTS1-AS1 INTS10 LPL LOC100128993
nsv1033511	Chr.8:19893788 - 20767580 on Build GRCh38	Gain	SLC18A1 LZTS1 ATP6V1B2 LZTS1-AS1 LPL

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

secondary carrier transporter

Gene Ontology Categories:

Process(es)

drug transmembrane transport
chemical synaptic transmission
aminergic neurotransmitter loading into synaptic vesicle
monoamine transport
positive regulation of dopamine secretion
serotonin uptake
negative regulation of serotonin uptake
cellular response to lithium ion

Function(s)

monoamine transmembrane transporter activity
serotonin transmembrane transporter activity
drug transmembrane transporter activity
enzyme binding