Hs03074378_cn

• Gene Symbol: MCM2
• Assay Reference Genome Location: Chr.3:127615849 on build GRCh38
• Cytoband: 3q21.3

Target Gene Details

• Entrez Gene ID: 4171
• Gene Name: minichromosome maintenance complex component 2
• Gene Aliases: BM28, CCNL1, CDCL1, D3S3194, DFNA70, MITOTIN, cdc19
• Location: Chr.3:127598357-127622436 on Build GRCh38
• Assay Gene Location: Overlaps Intron 8 - Exon 9

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
MCM2	NM_004526.3			NP_004517.2
	NR_073375.1
	AK128291.1
	AK299934.1
	AK304204.1
	AK309335.1
	BC006165.1
	BC007670.2			AAH07670.2
	BC007938.2			AAH07938.2
	BC014272.2			AAH14272.2
	BC017258.2			AAH17258.2
	BC017490.1			AAH17490.2
	BC030131.2			AAH30131.2
	BT009734.1			AAP88736.1
	D21063.1
	D83987.1			BAA12177.1
	X67334.1			CAA47749.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv8563n54	Chr.3:127543914 - 127685471 on Build GRCh38	Loss	TPRA1 ABTB1 PODXL2 MCM2 MIR7976 MIR6825

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

DNA metabolism protein

Gene Ontology Categories:

Process(es)

G1/S transition of mitotic cell cycle
DNA replication
DNA unwinding involved in DNA replication
DNA replication initiation
nucleosome assembly
cell cycle
cellular response to interleukin-4

Function(s)

DNA binding
DNA helicase activity
DNA replication origin binding
protein binding
ATP binding
enzyme binding
histone binding
metal ion binding