Hs03329831_cn

• Gene Symbol: DFFA
• Assay Reference Genome Location: Chr.1:10471314 on build GRCh38
• Cytoband: 1p36.22

Target Gene Details

• Entrez Gene ID: 1676
• Gene Name: DNA fragmentation factor subunit alpha
• Gene Aliases: DFF-45, DFF1, ICAD
• Location: Chr.1:10460531-10472556 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
DFFA	NM_004401.2			NP_004392.1
	NM_213566.1			NP_998731.1
	AF087573.1			AAD32953.1
	AF103799.1			AAF02419.1
	AK222546.1			BAD96266.1
	AK313317.1
	AU121791.1
	BC000037.2			AAH00037.1
	BC007112.1			AAH07112.1
	BC007721.2			AAH07721.1
	BT006980.1			AAP35626.1
	U91985.1			AAC51249.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2764192	Chr.1:10323676 - 10534129 on Build GRCh38	Gain	PEX14 PGD CORT APITD1 KIF1B DFFA APITD1-CORT
esv2758920	Chr.1:10178012 - 10522497 on Build GRCh38	Gain+Loss	PEX14 PGD CORT MIR1273D APITD1 KIF1B DFFA APITD1-CORT UBE4B

More Information

Additional Information:

For this assay, SNP(s) [rs76676818] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

apoptotic DNA fragmentation
positive regulation of apoptotic process
thymocyte apoptotic process
negative regulation of execution phase of apoptosis
negative regulation of apoptotic DNA fragmentation

Function(s)

protein binding