Hs03444967_cn

• Gene Symbol: POLR1A
• Assay Reference Genome Location: Chr.2:86037098 on build GRCh38
• Cytoband: 2p11.2

Target Gene Details

• Entrez Gene ID: 25885
• Gene Name: RNA polymerase I subunit A
• Gene Aliases: A190, AFDCIN, RPA1, RPA194, RPO1-4, RPO14
• Location: Chr.2:86026328-86106155 on Build GRCh38
• Assay Gene Location: Within Intron 27

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
POLR1A	NM_015425.4			NP_056240.2
	AK025568.1			BAB15171.1
	AK294447.1
	AK302458.1
	AK304131.1
	BC017115.1
	BC117173.1
	BC126303.1
	BC143345.1
	U33460.1			AAC99959.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2751903	Chr.2:86026419 - 86278330 on Build GRCh38	Gain	REEP1 IMMT MRPL35 SNORD94 PTCD3 POLR1A MIR4779

More Information

Additional Information:

For this assay, SNP(s) [rs74482159] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

DNA-directed RNA polymerase

Gene Ontology Categories:

Process(es)

transcription initiation from RNA polymerase I promoter
transcription elongation from RNA polymerase I promoter
termination of RNA polymerase I transcription
positive regulation of gene expression, epigenetic

Function(s)

RNA polymerase I activity
DNA binding
protein binding
zinc ion binding