Hs03470627_cn

• Gene Symbol: TATDN2
• Assay Reference Genome Location: Chr.3:10273904 on build GRCh38
• Cytoband: 3p25.3

Target Gene Details

• Entrez Gene ID: 9797
• Gene Name: TatD DNase domain containing 2
• Gene Aliases: -
• Location: Chr.3:10248493-10281222 on Build GRCh38
• Assay Gene Location: Within Intron 4

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TATDN2	NM_014760.3			NP_055575.3
	AK289794.1
	BC090935.1			AAH90935.1
	BC101770.1			AAI01771.1
	BC101776.1			AAI01777.1
	D86972.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv436362	Chr.3:10048344 - 11860564 on Build GRCh38	Deletion	VHL FANCD2OS MIR378B SEC13 GHRLOS VGLL4 TAMM41 GHRL ATP2B2-IT2 MIR885 BRK1 FANCD2 HRH1 LINC00606 TATDN2 SLC6A11 SLC6A1-AS1 SLC6A1 IRAK2 LOC101927467 ATP2B2 LINC00852 ATG7
nsv589650	Chr.3:10260488 - 10294102 on Build GRCh38	Loss	TATDN2 GHRLOS LINC00852 GHRL
dgv762e201	Chr.3:10008967 - 11913136 on Build GRCh38	Deletion	VHL FANCD2OS MIR378B CIDECP TAMM41 MIR885 BRK1 SLC6A11 SLC6A1 IRAK2 LOC101927467 ATG7 LOC401052 SEC13 GHRLOS EMC3 VGLL4 GHRL ATP2B2-IT2 FANCD2 HRH1 LINC00606 TATDN2 SLC6A1-AS1 FANCD2P2 ATP2B2 LINC00852
nsv1121603	Chr.3:10071433 - 11889279 on Build GRCh38	Deletion	VHL FANCD2OS MIR378B SEC13 GHRLOS VGLL4 TAMM41 GHRL ATP2B2-IT2 MIR885 BRK1 FANCD2 HRH1 LINC00606 TATDN2 SLC6A11 SLC6A1-AS1 SLC6A1 IRAK2 FANCD2P2 LOC101927467 ATP2B2 LINC00852 ATG7
nsv236904	Chr.3:10266949 - 10274997 on Build GRCh38	Deletion	TATDN2
nsv436869	Chr.3:10064456 - 11877985 on Build GRCh38	Insertion	VHL FANCD2OS MIR378B SEC13 GHRLOS VGLL4 TAMM41 GHRL ATP2B2-IT2 MIR885 BRK1 FANCD2 HRH1 LINC00606 TATDN2 SLC6A11 SLC6A1-AS1 SLC6A1 IRAK2 FANCD2P2 LOC101927467 ATP2B2 LINC00852 ATG7
nsv1073204	Chr.3:9996548 - 11875005 on Build GRCh38	Deletion	VHL FANCD2OS MIR378B EMC3-AS1 CIDECP TAMM41 MIR885 BRK1 SLC6A11 SLC6A1 IRAK2 LOC101927467 ATG7 LOC401052 SEC13 GHRLOS EMC3 VGLL4 GHRL ATP2B2-IT2 FANCD2 HRH1 LINC00606 TATDN2 SLC6A1-AS1 FANCD2P2 ATP2B2 LINC00852

More Information

Additional Information:

For this assay, SNP(s) [rs149894952] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

DNA catabolic process
IRE1-mediated unfolded protein response
nucleic acid phosphodiester bond hydrolysis

Function(s)

deoxyribonuclease activity
endodeoxyribonuclease activity, producing 5'-phosphomonoesters
metal ion binding