Hs03483507_cn

• Gene Symbol: MKRN2
• Assay Reference Genome Location: Chr.3:12573081 on build GRCh38
• Cytoband: 3p25.2

Target Gene Details

• Entrez Gene ID: 23609
• Gene Name: makorin ring finger protein 2
• Gene Aliases: HSPC070, RNF62
• Location: Chr.3:12557014-12583713 on Build GRCh38
• Assay Gene Location: Within Intron 4

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
MKRN2	NM_001271707.1			NP_001258636.1
	NM_014160.4			NP_054879.3
	AF302084.1			AAG30426.1
	AK091318.1
	AK298463.1
	AL834512.1			CAD39168.1
	BC001799.2			AAH01799.2
	BC015715.1			AAH15715.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3575548	Chr.3:12521381 - 12631860 on Build GRCh38	Gain	MKRN2OS RAF1 TSEN2 MKRN2
nsv1000995	Chr.3:12308425 - 12594756 on Build GRCh38	Gain	MKRN2OS PPARG RAF1 TSEN2 MKRN2
nsv1147269	Chr.3:11914420 - 12871937 on Build GRCh38	Deletion	TIMP4 CAND2 MKRN2OS PPARG RPL32 SYN2 RAF1 SNORA7A TSEN2 TMEM40 MKRN2
nsv1112379	Chr.3:11914395 - 12871920 on Build GRCh38	Deletion	TIMP4 CAND2 MKRN2OS PPARG RPL32 SYN2 RAF1 SNORA7A TSEN2 TMEM40 MKRN2
esv2751977	Chr.3:12452779 - 12887049 on Build GRCh38	Gain	CAND2 MKRN2OS PPARG RPL32 RAF1 SNORA7A TSEN2 TMEM40 LOC105376955 MKRN2
dgv850e199	Chr.3:11914188 - 12872013 on Build GRCh38	Deletion	TIMP4 CAND2 MKRN2OS PPARG RPL32 SYN2 RAF1 SNORA7A TSEN2 TMEM40 MKRN2
dgv763e201	Chr.3:11909121 - 12871926 on Build GRCh38	Deletion	TIMP4 CAND2 MKRN2OS PPARG RPL32 SYN2 RAF1 SNORA7A TSEN2 TMEM40 MKRN2

More Information

Additional Information:

For this assay, SNP(s) [rs113105671] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

ubiquitin-protein ligase

Gene Ontology Categories:

Process(es)

biological_process
protein ubiquitination

Function(s)

protein binding
zinc ion binding
ligase activity
poly(A) RNA binding