Hs03533070_cn

• Gene Symbol: APBB2
• Assay Reference Genome Location: Chr.4:40820259 on build GRCh38
• Cytoband: 4p14

Target Gene Details

• Entrez Gene ID: 323
• Gene Name: amyloid beta precursor protein binding family B member 2
• Gene Aliases: FE65L, FE65L1
• Location: Chr.4:40810027-41216714 on Build GRCh38
• Assay Gene Location: Within Intron 23

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
APBB2	NM_001166050.1			NP_001159522.1
	NM_001166051.1			NP_001159523.1
	NM_001166052.1			NP_001159524.1
	NM_001166053.1			NP_001159525.1
	NM_001166054.1			NP_001159526.1
	NM_004307.1			NP_004298.1
	NM_173075.4			NP_775098.2
	XM_005248101.3			XP_005248158.1
	XM_006714005.3			XP_006714068.1
	XM_006714007.3			XP_006714070.1
	XM_006714008.3			XP_006714071.1
	XM_006714009.3			XP_006714072.1
	XM_006714010.3			XP_006714073.1
	XM_006714011.3			XP_006714074.1
	XM_006714012.3			XP_006714075.1
	XM_011513686.2			XP_011511988.1
	XM_011513687.2			XP_011511989.1
	XM_017008142.1			XP_016863631.1
	XM_017008143.1			XP_016863632.1
	XM_017008144.1			XP_016863633.1
	XM_017008145.1			XP_016863634.1
	XM_017008146.1			XP_016863635.1
	XM_017008147.1			XP_016863636.1
	XM_017008148.1			XP_016863637.1
	XM_017008149.1			XP_016863638.1
	XM_017008150.1			XP_016863639.1
	XM_017008151.1			XP_016863640.1
	XM_017008152.1			XP_016863641.1
	XM_017008153.1			XP_016863642.1
	XM_017008154.1			XP_016863643.1
	XM_017008155.1			XP_016863644.1
	XM_017008156.1			XP_016863645.1
	XM_017008157.1			XP_016863646.1
	XM_017008158.1			XP_016863647.1
	AK226179.1
	AK289838.1
	AK299800.1
	AK304247.1
	BC027946.1			AAH27946.2
	BC088372.1			AAH88372.1
	BU184203.1
	BX440903.2
	CX782504.1
	KU177906.1
	KU177907.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv1477e212	Chr.4:40820049 - 40825701 on Build GRCh38	Gain	APBB2
nsv10486	Chr.4:40747595 - 40935088 on Build GRCh38	Gain	APBB2 NSUN7
nsv4307	Chr.4:40796057 - 40823222 on Build GRCh38	Deletion	APBB2 NSUN7
nsv829912	Chr.4:40720092 - 40840600 on Build GRCh38	Loss	APBB2 NSUN7

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

neuron migration
regulation of transcription, DNA-templated
cell cycle arrest
axon guidance
extracellular matrix organization
negative regulation of cell growth
intracellular signal transduction
positive regulation of apoptotic process
negative regulation of apoptotic process

Function(s)

beta-amyloid binding
protein binding
transcription factor binding