Hs03627961_cn

• Gene Symbol: POLR2J
• Assay Reference Genome Location: Chr.7:102473909 on build GRCh38
• Cytoband: 7q22.1

Target Gene Details

• Entrez Gene ID: 5439
• Gene Name: RNA polymerase II subunit J
• Gene Aliases: POLR2J1, RPB11, RPB11A, RPB11m, hRPB14
• Location: Chr.7:102473100-102478999 on Build GRCh38
• Assay Gene Location: Within Exon 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
POLR2J	NM_006234.4			NP_006225.1
	XM_005250452.4	3	909	XP_005250509.1
	XM_017012353.1			XP_016867842.1
	AK290515.1
	BC024165.1			AAH24165.1
	BC065711.1			AAH65711.1
	BC139902.1
	BC141830.1
	BM545237.1
	BM791979.1
	L37127.1			AAD05361.1
	X82385.1			CAA57785.1
	X98433.1			CAA67075.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv831083	Chr.7:102340560 - 102655422 on Build GRCh38	Loss	MIR4467 LOC100630923 PRKRIP1 LOC102724229 LRWD1 LOC107983993 SPDYE2 MIR548O RASA4B POLR2J SPDYE2B RASA4 UPK3BL POLR2J2 LOC100289561 ORAI2 POLR2J3 MIR5090 ALKBH4 SPDYE6
nsv482111	Chr.7:102473103 - 102478934 on Build GRCh38	Gain	POLR2J LRWD1
dgv23n31	Chr.7:102473939 - 102777602 on Build GRCh38	Gain	RASA4B POLR2J SPDYE2B RASA4 FBXL13 FAM185A UPK3BL POLR2J2 LOC102724229 POLR2J3 LOC107983993 SPDYE2
nsv608005	Chr.7:102473640 - 102690366 on Build GRCh38	Gain	RASA4B POLR2J SPDYE2B RASA4 UPK3BL POLR2J2 LOC102724229 POLR2J3 LOC107983993 SPDYE2
dgv11541n54	Chr.7:102473462 - 102646638 on Build GRCh38	Loss	RASA4B POLR2J RASA4 UPK3BL POLR2J2 LOC102724229 POLR2J3 LOC107983993 SPDYE2
nsv8192	Chr.7:102450605 - 102692752 on Build GRCh38	Gain	MIR4467 LOC102724229 LRWD1 LOC107983993 SPDYE2 RASA4B POLR2J SPDYE2B RASA4 UPK3BL POLR2J2 ORAI2 POLR2J3 MIR5090 ALKBH4
esv27624	Chr.7:102472919 - 102691417 on Build GRCh38	Gain+Loss	RASA4B POLR2J SPDYE2B RASA4 UPK3BL POLR2J2 LOC102724229 LRWD1 POLR2J3 LOC107983993 SPDYE2
nsv428182	Chr.7:102257460 - 102735503 on Build GRCh38	Gain	MIR4467 SH2B2 LOC100630923 PRKRIP1 LOC102724229 LRWD1 LOC107983993 SPDYE2 MIR4285 MIR548O RASA4B POLR2J SPDYE2B RASA4 FBXL13 UPK3BL POLR2J2 CUX1 LOC100289561 ORAI2 POLR2J3 MIR5090 ALKBH4 SPDYE6
dgv6538n100	Chr.7:102171110 - 103063688 on Build GRCh38	Gain	LOC100630923 FAM185A MIR548O SPDYE2B RASA4 FBXL13 POLR2J2 LRRC17 POLR2J3 NFE4 MIR4467 SH2B2 PRKRIP1 LOC102724229 LRWD1 LOC107983993 SPDYE2 MIR4285 RASA4B POLR2J UPK3BL CUX1 LOC100289561 ORAI2 MIR5090 ALKBH4 SPDYE6
nsv5879	Chr.7:102450321 - 102747356 on Build GRCh38	Deletion	MIR4467 LOC102724229 LRWD1 LOC107983993 SPDYE2 RASA4B POLR2J SPDYE2B RASA4 FBXL13 UPK3BL POLR2J2 ORAI2 POLR2J3 MIR5090 ALKBH4

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

DNA-directed RNA polymerase, RNA metabolism protein, nucleic acid metabolism protein

Gene Ontology Categories:

Process(es)

mRNA splicing, via spliceosome
transcription-coupled nucleotide-excision repair
transcription from RNA polymerase II promoter
transcription initiation from RNA polymerase II promoter
transcription elongation from RNA polymerase II promoter
7-methylguanosine mRNA capping
fibroblast growth factor receptor signaling pathway
gene expression
gene silencing by RNA
somatic stem cell population maintenance
snRNA transcription from RNA polymerase II promoter
positive regulation of viral transcription

Function(s)

RNA polymerase II activity
DNA binding
DNA-directed RNA polymerase activity
protein binding
LRR domain binding
protein dimerization activity