Hs03664883_cn

• Gene Symbol: SLC18A1
• Assay Reference Genome Location: Chr.8:20148143 on build GRCh38
• Cytoband: 8p21.3

Target Gene Details

• Entrez Gene ID: 6570
• Gene Name: solute carrier family 18 member A1
• Gene Aliases: CGAT, VAT1, VMAT1
• Location: Chr.8:20144855-20183206 on Build GRCh38
• Assay Gene Location: Within Intron 13

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SLC18A1	NM_001135691.2			NP_001129163.1
	NM_001142324.1			NP_001135796.1
	NM_001142325.1			NP_001135797.1
	NM_003053.3			NP_003044.1
	XM_011544625.1			XP_011542927.1
	XM_011544626.1			XP_011542928.1
	XM_011544627.1			XP_011542929.1
	AK313720.1
	BC006317.2			AAH06317.1
	BC009387.2			AAH09387.1
	U39905.1			AAC50472.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv438045	Chr.8:20135591 - 20165660 on Build GRCh38	Loss	SLC18A1
nsv1030738	Chr.8:20131683 - 20164639 on Build GRCh38	Gain	SLC18A1
nsv508498	Chr.8:20127378 - 20174629 on Build GRCh38	Deletion	SLC18A1
nsv8312	Chr.8:20140652 - 20149500 on Build GRCh38	Gain	SLC18A1
esv3891373	Chr.8:20127871 - 20164378 on Build GRCh38	Loss	SLC18A1
esv3616559	Chr.8:20127120 - 20166631 on Build GRCh38	Loss	SLC18A1
nsv824563	Chr.8:20127252 - 20168579 on Build GRCh38	Loss	SLC18A1
nsv610759	Chr.8:19704486 - 20211331 on Build GRCh38	Gain	ATP6V1B2 INTS10 LPL SLC18A1 CSGALNACT1
nsv522185	Chr.8:19097292 - 20497802 on Build GRCh38	Gain	LZTS1-AS1 ATP6V1B2 INTS10 LPL SLC18A1 LOC100128993 SH2D4A CSGALNACT1 LZTS1
esv2759602	Chr.8:20129060 - 20172092 on Build GRCh38	Loss	SLC18A1
nsv1033511	Chr.8:19893788 - 20767580 on Build GRCh38	Gain	LZTS1-AS1 ATP6V1B2 LPL SLC18A1 LZTS1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

secondary carrier transporter

Gene Ontology Categories:

Process(es)

drug transmembrane transport
chemical synaptic transmission
aminergic neurotransmitter loading into synaptic vesicle
monoamine transport
positive regulation of dopamine secretion
serotonin uptake
negative regulation of serotonin uptake
cellular response to lithium ion

Function(s)

monoamine transmembrane transporter activity
serotonin transmembrane transporter activity
drug transmembrane transporter activity
enzyme binding