Hs03679074_cn

• Gene Symbol: TUSC3
• Assay Reference Genome Location: Chr.8:15541276 on build GRCh38
• Cytoband: 8p22

Target Gene Details

• Entrez Gene ID: 7991
• Gene Name: tumor suppressor candidate 3
• Gene Aliases: D8S1992, M33, MRT22, MRT7, N33, OST3A
• Location: Chr.8:15540087-15766649 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TUSC3	NM_006765.3			NP_006756.2
	NM_178234.2			NP_839952.1
	BC010370.1			AAH10370.1
	BT020002.1			AAV38805.1
	DA796279.1
	U42349.1			AAB18374.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1161734	Chr.8:15533647 - 15548772 on Build GRCh38	Deletion	TUSC3
esv3572557	Chr.8:15469077 - 15543402 on Build GRCh38	Loss	TUSC3
nsv437055	Chr.8:15398926 - 15806828 on Build GRCh38	Loss	TUSC3
nsv6089	Chr.8:15538984 - 15565828 on Build GRCh38	Deletion	TUSC3
esv2759598	Chr.8:14768691 - 15907197 on Build GRCh38	Loss	SGCZ TUSC3 MIR383
esv3616403	Chr.8:15528780 - 15600263 on Build GRCh38	Loss	TUSC3
dgv248e55	Chr.8:14773418 - 15806518 on Build GRCh38	Loss	SGCZ TUSC3 MIR383
nsv517314	Chr.8:15531057 - 15554099 on Build GRCh38	Loss	TUSC3
nsv610466	Chr.8:14469128 - 15809390 on Build GRCh38	Loss	SGCZ TUSC3 MIR383
nsv818605	Chr.8:14773392 - 15802730 on Build GRCh38	Loss	SGCZ TUSC3 MIR383
nsv610524	Chr.8:15419198 - 15568674 on Build GRCh38	Loss	TUSC3
nsv1029399	Chr.8:14978756 - 16296799 on Build GRCh38	Gain	MSR1 SGCZ TUSC3
nsv8298	Chr.8:14772387 - 15806223 on Build GRCh38	Gain+Loss	SGCZ TUSC3 MIR383
nsv1020054	Chr.8:15444894 - 15812092 on Build GRCh38	Gain	TUSC3
nsv465554	Chr.8:15537635 - 15554099 on Build GRCh38	Loss	TUSC3

More Information

Additional Information:

For this assay, SNP(s) [rs112256089] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

glycosyltransferase

Gene Ontology Categories:

Process(es)

protein N-linked glycosylation
magnesium ion transport
protein N-linked glycosylation via asparagine
cognition
transmembrane transport
magnesium ion transmembrane transport

Function(s)

dolichyl-diphosphooligosaccharide-protein glycotransferase activity
magnesium ion transmembrane transporter activity