Hs03697384_cn

• Gene Symbol: MSR1
• Assay Reference Genome Location: Chr.8:16111975 on build GRCh38
• Cytoband: 8p22

Target Gene Details

• Entrez Gene ID: 4481
• Gene Name: macrophage scavenger receptor 1
• Gene Aliases: CD204, SCARA1, SR-A, SRA, phSR1, phSR2
• Location: Chr.8:16107878-16192791 on Build GRCh38
• Assay Gene Location: Within Intron 10

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
MSR1	NM_138715.2			NP_619729.1
	NM_138716.2			NP_619730.1
	AF037351.1			AAC09251.1
	AK293217.1
	BC063878.1			AAH63878.1
	D90187.1			BAA14208.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv831241	Chr.8:16025262 - 16146736 on Build GRCh38	Gain+Loss	MSR1
esv3572569	Chr.8:16110908 - 16114175 on Build GRCh38	Loss	MSR1
nsv1031894	Chr.8:16084388 - 16157888 on Build GRCh38	Gain	MSR1
dgv1382e214	Chr.8:16087881 - 16166383 on Build GRCh38	Loss	MSR1
esv3616432	Chr.8:16089605 - 16164358 on Build GRCh38	Gain	MSR1
nsv1024623	Chr.8:16017012 - 16146893 on Build GRCh38	Gain	MSR1
esv2764093	Chr.8:16092468 - 16167255 on Build GRCh38	Gain+Loss	MSR1
esv3543130	Chr.8:16087492 - 16166491 on Build GRCh38	Deletion	MSR1
dgv249e55	Chr.8:16075727 - 16163959 on Build GRCh38	Loss	MSR1
nsv1023558	Chr.8:16105571 - 16127519 on Build GRCh38	Gain	MSR1
dgv7109n100	Chr.8:16086558 - 16167255 on Build GRCh38	Loss	MSR1
dgv12024n54	Chr.8:16103682 - 16163959 on Build GRCh38	Loss	MSR1
dgv2050e212	Chr.8:16086798 - 16166712 on Build GRCh38	Loss	MSR1
esv3891356	Chr.8:16092262 - 16163959 on Build GRCh38	Loss	MSR1
esv3576529	Chr.8:15792094 - 16396053 on Build GRCh38	Gain	MSR1
esv3616422	Chr.8:16021420 - 16139525 on Build GRCh38	Loss	MSR1
nsv610576	Chr.8:16070177 - 16381359 on Build GRCh38	Gain	MSR1
nsv1029399	Chr.8:14978756 - 16296799 on Build GRCh38	Gain	TUSC3 MSR1 SGCZ
esv3616424	Chr.8:16023868 - 16498645 on Build GRCh38	Gain	MSR1
esv2668117	Chr.8:16087842 - 16166407 on Build GRCh38	Deletion	MSR1
esv3572572	Chr.8:16059385 - 16136348 on Build GRCh38	Loss	MSR1
dgv12022n54	Chr.8:16085204 - 16171983 on Build GRCh38	Loss	MSR1

More Information

Additional Information:

For this assay, SNP(s) [rs145329024,rs78105795] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

serine protease

Gene Ontology Categories:

Process(es)

receptor-mediated endocytosis
positive regulation of macrophage derived foam cell differentiation
positive regulation of cholesterol storage
cholesterol transport
plasma lipoprotein particle clearance
lipoprotein transport
cellular response to organic cyclic compound

Function(s)

scavenger receptor activity
protein binding
low-density lipoprotein particle binding