Hs03840984_cn

• Gene Symbol: FGD4
• Assay Reference Genome Location: Chr.12:32404863 on build GRCh38
• Cytoband: 12p11.21

Target Gene Details

• Entrez Gene ID: 121512
• Gene Name: FYVE, RhoGEF and PH domain containing 4
• Gene Aliases: CMT4H, FRABP, ZFYVE6
• Location: Chr.12:32399523-32646050 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
FGD4	XM_005253304.4			XP_005253361.1
	XM_005253309.1			XP_005253366.1
	XM_017018803.1			XP_016874292.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv558189	Chr.12:32402912 - 32449145 on Build GRCh38	Gain	FGD4
nsv469346	Chr.12:32378286 - 32434531 on Build GRCh38	Loss	BICD1 FGD4
esv3629076	Chr.12:32401472 - 32407015 on Build GRCh38	Loss	FGD4
esv2668802	Chr.12:32401424 - 32407159 on Build GRCh38	Deletion	FGD4
esv2751096	Chr.12:32127406 - 32549850 on Build GRCh38	Gain	BICD1 FGD4
esv3580220	Chr.12:32404645 - 32462728 on Build GRCh38	Loss	FGD4
nsv558171	Chr.12:32134325 - 32406759 on Build GRCh38	Gain	BICD1 FGD4

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

G-protein modulator, protein-binding activity modulator, guanyl-nucleotide exchange factor

Gene Ontology Categories:

Process(es)

cytoskeleton organization
regulation of cell shape
actin cytoskeleton organization
regulation of Rho protein signal transduction
positive regulation of apoptotic process
regulation of GTPase activity
positive regulation of GTPase activity
filopodium assembly
regulation of small GTPase mediated signal transduction

Function(s)

actin binding
guanyl-nucleotide exchange factor activity
Rho guanyl-nucleotide exchange factor activity
small GTPase binding
metal ion binding