Hs03904676_cn

• Gene Symbol: CYP1A1
• Assay Reference Genome Location: Chr.15:74724775 on build GRCh38
• Cytoband: 15q24.1

Target Gene Details

• Entrez Gene ID: 1543
• Gene Name: cytochrome P450 family 1 subfamily A member 1
• Gene Aliases: AHH, AHRR, CP11, CYP1, CYPIA1, P1-450, P450-C, P450DX
• Location: Chr.15:74719542-74725610 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CYP1A1	NM_000499.4			NP_000490.1
	NM_001319216.1			NP_001306145.1
	NM_001319217.1			NP_001306146.1
	XM_017021953.1			XP_016877442.1
	AK223108.1			BAD96828.1
	AK223113.1			BAD96833.1
	AK310810.1
	AK313880.1
	AM233517.1
	AM233518.1
	AM233519.1
	AM233520.1
	AM236046.1
	AM236047.1
	AY871801.1
	BC023019.1			AAH23019.1
	DA693879.1
	K03191.1			AAA52139.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv833055	Chr.15:74696003 - 74873947 on Build GRCh38	Loss	LMAN1L SCAMP2 CSK MIR4513 CPLX3 MIR6882 CYP1A1 EDC3 ULK3 CYP1A2
esv3636907	Chr.15:74721538 - 74745196 on Build GRCh38	Loss	CYP1A1
nsv817698	Chr.15:74596822 - 74727108 on Build GRCh38	Gain	ARID3B CLK3 CYP1A1 LOC102723750 EDC3
esv2763106	Chr.15:74722123 - 74741845 on Build GRCh38	Loss	CYP1A1
nsv1121512	Chr.15:72670085 - 75273877 on Build GRCh38	Deletion	ISLR2 FAM219B RPP25 CPLX3 SCAMP5 PPCDC CYP1A1 EDC3 CLK3 UBL7 MIR4513 TBC1D21 LOC101929333 CD276 ULK3 C15orf59-AS1 ARID3B SEMA7A MIR6881 NPTN-IT1 HCN4 LOXL1-AS1 C15orf59 NEO1 COX5A GOLGA6C BBS4 C15orf39 LOC105376731 NPTN LOC107984728 REC114 CYP1A2 LOC283731 ADPGK-AS1 ADPGK LMAN1L CCDC33 UBL7-AS1 HIGD2B LOC102723750 LOC729739 LOC732265 PML CSK CYP11A1 STOML1 STRA6 SCAMP2 LOXL1 ISLR MPI MIR6882 GOLGA6A

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

response to hypoxia
porphyrin-containing compound metabolic process
aging
cell proliferation
amine metabolic process
response to wounding
response to virus
response to nematode
response to herbicide
ethylene metabolic process
embryo development ending in birth or egg hatching
coumarin metabolic process
flavonoid metabolic process
response to iron(III) ion
insecticide metabolic process
drug metabolic process
dibenzo-p-dioxin catabolic process
epoxygenase P450 pathway
response to food
response to lipopolysaccharide
response to vitamin A
response to immobilization stress
vitamin D metabolic process
response to drug
9-cis-retinoic acid biosynthetic process
camera-type eye development
response to antibiotic
response to arsenic-containing substance
digestive tract development
hydrogen peroxide biosynthetic process
response to hyperoxia
oxidation-reduction process
maternal process involved in parturition
hepatocyte differentiation
demethylation
cellular response to organic cyclic compound
omega-hydroxylase P450 pathway
positive regulation of G1/S transition of mitotic cell cycle

Function(s)

monooxygenase activity
iron ion binding
protein binding
steroid hydroxylase activity
oxidoreductase activity
oxidoreductase activity, acting on diphenols and related substances as donors
flavonoid 3'-monooxygenase activity
oxygen binding
enzyme binding
heme binding
demethylase activity
aromatase activity
vitamin D 24-hydroxylase activity