Hs03907273_cn

• Gene Symbol: CYP1A1
• Assay Reference Genome Location: Chr.15:74723918 on build GRCh38
• Cytoband: 15q24.1

Target Gene Details

• Entrez Gene ID: 1543
• Gene Name: cytochrome P450 family 1 subfamily A member 1
• Gene Aliases: AHH, AHRR, CP11, CYP1, CYPIA1, P1-450, P450-C, P450DX
• Location: Chr.15:74719542-74725610 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CYP1A1	NM_000499.4			NP_000490.1
	NM_001319216.1			NP_001306145.1
	NM_001319217.1			NP_001306146.1
	XM_017021953.1			XP_016877442.1
	AK223108.1			BAD96828.1
	AK223113.1			BAD96833.1
	AK310810.1
	AK313880.1
	AM233517.1
	AM233518.1
	AM233519.1
	AM233520.1
	AM236046.1
	AM236047.1
	AY871801.1
	BC023019.1			AAH23019.1
	DA693879.1
	K03191.1			AAA52139.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv833055	Chr.15:74696003 - 74873947 on Build GRCh38	Loss	CPLX3 MIR4513 SCAMP2 ULK3 MIR6882 EDC3 CYP1A1 CSK CYP1A2 LMAN1L
esv3636907	Chr.15:74721538 - 74745196 on Build GRCh38	Loss	CYP1A1
nsv817698	Chr.15:74596822 - 74727108 on Build GRCh38	Gain	ARID3B EDC3 CYP1A1 LOC102723750 CLK3
esv2763106	Chr.15:74722123 - 74741845 on Build GRCh38	Loss	CYP1A1
nsv1121512	Chr.15:72670085 - 75273877 on Build GRCh38	Deletion	LOC105376731 MPI CYP11A1 NPTN SCAMP5 LOC283731 COX5A CD276 LMAN1L UBL7-AS1 RPP25 CPLX3 ADPGK FAM219B PML SEMA7A LOC101929333 NPTN-IT1 LOXL1 CYP1A2 MIR4513 C15orf59 ARID3B BBS4 CCDC33 PPCDC C15orf39 HIGD2B ADPGK-AS1 MIR6882 EDC3 GOLGA6A CYP1A1 LOC102723750 C15orf59-AS1 REC114 LOXL1-AS1 NEO1 ULK3 UBL7 ISLR2 HCN4 STRA6 GOLGA6C LOC729739 SCAMP2 STOML1 LOC107984728 LOC732265 MIR6881 CSK TBC1D21 ISLR CLK3

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

response to hypoxia
porphyrin-containing compound metabolic process
aging
cell proliferation
amine metabolic process
response to wounding
response to virus
response to nematode
response to herbicide
ethylene metabolic process
embryo development ending in birth or egg hatching
coumarin metabolic process
flavonoid metabolic process
response to iron(III) ion
insecticide metabolic process
drug metabolic process
dibenzo-p-dioxin catabolic process
epoxygenase P450 pathway
response to food
response to lipopolysaccharide
response to vitamin A
response to immobilization stress
vitamin D metabolic process
response to drug
9-cis-retinoic acid biosynthetic process
camera-type eye development
response to antibiotic
response to arsenic-containing substance
digestive tract development
hydrogen peroxide biosynthetic process
response to hyperoxia
oxidation-reduction process
maternal process involved in parturition
hepatocyte differentiation
demethylation
cellular response to organic cyclic compound
omega-hydroxylase P450 pathway
positive regulation of G1/S transition of mitotic cell cycle

Function(s)

monooxygenase activity
iron ion binding
protein binding
steroid hydroxylase activity
oxidoreductase activity
oxidoreductase activity, acting on diphenols and related substances as donors
flavonoid 3'-monooxygenase activity
oxygen binding
enzyme binding
heme binding
demethylase activity
aromatase activity
vitamin D 24-hydroxylase activity