Hs03992496_cn

• Gene Symbol: CD226
• Assay Reference Genome Location: Chr.18:69866467 on build GRCh38
• Cytoband: 18q22.2

Target Gene Details

• Entrez Gene ID: 10666
• Gene Name: CD226 molecule
• Gene Aliases: DNAM-1, DNAM1, PTA1, TLiSA1
• Location: Chr.18:69860228-69962086 on Build GRCh38
• Assay Gene Location: Within Intron 11

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CD226	NM_001303618.1			NP_001290547.1
	NM_001303619.1			NP_001290548.1
	NM_006566.3			NP_006557.2
	XM_005266642.3			XP_005266699.1
	XM_005266643.3			XP_005266700.1
	XM_006722374.3			XP_006722437.1
	XM_017025524.1			XP_016881013.1
	XM_017025525.1			XP_016881014.1
	XM_017025526.1			XP_016881015.1
	XM_017025527.1			XP_016881016.1
	AJ537553.1			CAD61184.1
	AK313199.1
	BC074787.2			AAH74787.1
	GU935335.1
	GU935336.1
	U56102.1			AAC50560.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv32736	Chr.18:69135149 - 71678611 on Build GRCh38	Gain+Loss	LOC101060542 SOCS6 LOC101927481 DOK6 LINC01541 LOC105372179 CD226 GTSCR1 RTTN CCDC102B

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

cytokine production
positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
positive regulation of immunoglobulin mediated immune response
cell adhesion
homophilic cell adhesion via plasma membrane adhesion molecules
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
signal transduction
cell recognition
positive regulation of mast cell activation
positive regulation of natural killer cell mediated cytotoxicity
regulation of immune response
positive regulation of Fc receptor mediated stimulatory signaling pathway

Function(s)

receptor activity
integrin binding
protein binding
protein kinase binding
protein homodimerization activity
cell adhesion molecule binding