Hs04017730_cn

• Gene Symbol: KLC3
• Assay Reference Genome Location: Chr.19:45343000 on build GRCh38
• Cytoband: 19q13.32

Target Gene Details

• Entrez Gene ID: 147700
• Gene Name: kinesin light chain 3
• Gene Aliases: KLC2, KLC2L, KLCt, KNS2B
• Location: Chr.19:45340740-45351520 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
KLC3	NM_177417.2			NP_803136.2
	BC062998.1
	BC073841.1			AAH73841.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv833845	Chr.19:45308814 - 45457371 on Build GRCh38	Loss	CD3EAP CKM KLC3 PPP1R13L ERCC2 ERCC1 MIR6088
dgv29n64	Chr.19:45334011 - 45373709 on Build GRCh38	Gain	KLC3 ERCC2
esv3644502	Chr.19:45323147 - 45403933 on Build GRCh38	Gain	KLC3 PPP1R13L ERCC2
esv3644503	Chr.19:45335731 - 45345968 on Build GRCh38	Loss	KLC3
esv3644504	Chr.19:45342675 - 45373732 on Build GRCh38	Gain	KLC3 ERCC2
nsv458711	Chr.19:45323108 - 45408744 on Build GRCh38	Gain	CD3EAP KLC3 PPP1R13L ERCC2 ERCC1
nsv1063547	Chr.19:45322368 - 45400204 on Build GRCh38	Gain	CKM KLC3 PPP1R13L ERCC2
nsv833844	Chr.19:45181051 - 45384148 on Build GRCh38	Loss	MARK4 EXOC3L2 BLOC1S3 CKM KLC3 PPP1R13L ERCC2
nsv579868	Chr.19:45334025 - 45359625 on Build GRCh38	Gain	KLC3 ERCC2

More Information

Additional Information:

For this assay, SNP(s) [rs73940011] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

cytoskeletal protein, microtubule binding motor protein, microtubule or microtubule-binding cytoskeletal protein

Gene Ontology Categories:

Process(es)

axo-dendritic transport

Function(s)

microtubule motor activity
protein binding
microtubule binding
kinesin binding