Hs04026148_cn

• Gene Symbol: APC2
• Assay Reference Genome Location: Chr.19:1454301 on build GRCh38
• Cytoband: 19p13.3

Target Gene Details

• Entrez Gene ID: 10297
• Gene Name: APC2, WNT signaling pathway regulator
• Gene Aliases: APCL
• Location: Chr.19:1446268-1473244 on Build GRCh38
• Assay Gene Location: Within Intron 6

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
APC2	NM_005883.2			NP_005874.1
	XM_005259475.2			XP_005259532.1
	XM_006722607.2			XP_006722670.1
	XM_006722608.3			XP_006722671.2
	XM_006722609.3			XP_006722672.1
	XM_006722610.3			XP_006722673.2
	AB012162.1			BAA34611.1
	AF110334.1			AAD28183.1
	AF128222.1			AAF01784.1
	AJ012652.1			CAB61207.1
	AL078616.1
	BC032573.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv32942	Chr.19:1320268 - 1999205 on Build GRCh38	Gain+Loss	UQCR11 MBD3 ADAT3 KLF16 C19orf25 ATP8B3 REXO1 MUM1 TCF3 RPS15 NDUFS7 ABHD17A ONECUT3 DAZAP1 CSNK1G2-AS1 SCAMP4 MEX3D REEP6 LOC100288123 CSNK1G2 PLK5 MIR1909 ADAMTSL5 PCSK4 GAMT APC2 BTBD2
nsv578279	Chr.19:1413575 - 1530061 on Build GRCh38	Gain	DAZAP1 RPS15 PLK5 ADAMTSL5 PCSK4 APC2 C19orf25 REEP6
nsv833705	Chr.19:1380125 - 1544934 on Build GRCh38	Loss	DAZAP1 RPS15 PLK5 ADAMTSL5 PCSK4 GAMT APC2 NDUFS7 C19orf25 REEP6
esv2758743	Chr.19:951641 - 1544934 on Build GRCh38	Gain+Loss	CIRBP-AS1 ARID3A C19orf25 WDR18 CNN2 STK11 MUM1 CBARP RPS15 GRIN3B NDUFS7 SBNO2 TMEM259 C19orf24 LOC102725180 DAZAP1 ABCA7 POLR2E GPX4 MIDN REEP6 LOC105372235 ARHGAP45 PLK5 EFNA2 CIRBP ADAMTSL5 PCSK4 GAMT APC2 ATP5D RNU6-2
nsv953942	Chr.19:1371602 - 2057401 on Build GRCh38	Deletion	UQCR11 MBD3 MKNK2 ADAT3 KLF16 C19orf25 ATP8B3 REXO1 MUM1 TCF3 RPS15 NDUFS7 ABHD17A ONECUT3 DAZAP1 CSNK1G2-AS1 SCAMP4 MEX3D REEP6 LOC100288123 CSNK1G2 PLK5 MIR1909 ADAMTSL5 PCSK4 GAMT APC2 BTBD2
nsv470105	Chr.19:1444420 - 1526614 on Build GRCh38	Gain	PLK5 ADAMTSL5 PCSK4 APC2 C19orf25 REEP6

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

cell fate specification
negative regulation of microtubule depolymerization
pattern specification process
cell proliferation
Wnt signaling pathway
cell migration
negative regulation of catenin import into nucleus
regulation of cell differentiation
positive regulation of protein catabolic process
negative regulation of canonical Wnt signaling pathway

Function(s)

protein binding
beta-catenin binding
microtubule binding
gamma-catenin binding