Hs04029932_cn

• Gene Symbol: APC2
• Assay Reference Genome Location: Chr.19:1453993 on build GRCh38
• Cytoband: 19p13.3

Target Gene Details

• Entrez Gene ID: 10297
• Gene Name: APC2, WNT signaling pathway regulator
• Gene Aliases: APCL
• Location: Chr.19:1446268-1473244 on Build GRCh38
• Assay Gene Location: Within Intron 6

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
APC2	NM_005883.2			NP_005874.1
	XM_005259475.2			XP_005259532.1
	XM_006722607.2			XP_006722670.1
	XM_006722608.3			XP_006722671.2
	XM_006722609.3			XP_006722672.1
	XM_006722610.3			XP_006722673.2
	AB012162.1			BAA34611.1
	AF110334.1			AAD28183.1
	AF128222.1			AAF01784.1
	AJ012652.1			CAB61207.1
	AL078616.1
	BC032573.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv32942	Chr.19:1320268 - 1999205 on Build GRCh38	Gain+Loss	CSNK1G2-AS1 DAZAP1 TCF3 C19orf25 LOC100288123 PCSK4 ADAT3 ABHD17A MBD3 REXO1 APC2 PLK5 REEP6 ONECUT3 ADAMTSL5 BTBD2 NDUFS7 CSNK1G2 GAMT KLF16 SCAMP4 MEX3D UQCR11 RPS15 MUM1 MIR1909 ATP8B3
nsv578279	Chr.19:1413575 - 1530061 on Build GRCh38	Gain	PCSK4 DAZAP1 APC2 PLK5 REEP6 C19orf25 RPS15 ADAMTSL5
nsv833705	Chr.19:1380125 - 1544934 on Build GRCh38	Loss	PCSK4 NDUFS7 GAMT DAZAP1 APC2 PLK5 REEP6 C19orf25 RPS15 ADAMTSL5
esv2758743	Chr.19:951641 - 1544934 on Build GRCh38	Gain+Loss	C19orf24 GPX4 STK11 DAZAP1 RNU6-2 C19orf25 ABCA7 GRIN3B PCSK4 LOC102725180 APC2 ATP5D PLK5 REEP6 EFNA2 ADAMTSL5 CIRBP TMEM259 NDUFS7 LOC105372235 GAMT ARID3A CIRBP-AS1 WDR18 CBARP SBNO2 MIDN ARHGAP45 POLR2E CNN2 RPS15 MUM1
nsv953942	Chr.19:1371602 - 2057401 on Build GRCh38	Deletion	MKNK2 CSNK1G2-AS1 DAZAP1 TCF3 C19orf25 LOC100288123 PCSK4 ADAT3 ABHD17A MBD3 REXO1 APC2 PLK5 REEP6 ONECUT3 ADAMTSL5 BTBD2 NDUFS7 CSNK1G2 GAMT KLF16 SCAMP4 MEX3D UQCR11 RPS15 MUM1 MIR1909 ATP8B3
nsv470105	Chr.19:1444420 - 1526614 on Build GRCh38	Gain	PCSK4 APC2 PLK5 REEP6 C19orf25 ADAMTSL5

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

cell fate specification
negative regulation of microtubule depolymerization
pattern specification process
cell proliferation
Wnt signaling pathway
cell migration
negative regulation of catenin import into nucleus
regulation of cell differentiation
positive regulation of protein catabolic process
negative regulation of canonical Wnt signaling pathway

Function(s)

protein binding
beta-catenin binding
microtubule binding
gamma-catenin binding