Hs04033519_cn

• Gene Symbol: RNASEH2A
• Assay Reference Genome Location: Chr.19:12811194 on build GRCh38
• Cytoband: 19p13.13

Target Gene Details

• Entrez Gene ID: 10535
• Gene Name: ribonuclease H2 subunit A
• Gene Aliases: AGS4, JUNB, RNASEHI, RNHIA, RNHL
• Location: Chr.19:12802054-12813648 on Build GRCh38
• Assay Gene Location: Within Intron 8

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
RNASEH2A	NM_006397.2			NP_006388.2
	XM_006722619.2			XP_006722682.1
	AK315327.1
	AY363912.1			AAQ64005.1
	BC011748.2			AAH11748.1
	BG825340.1
	BM664190.1
	CB240995.1
	CR456841.1			CAG33122.1
	Z97029.1			CAB09725.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv953977	Chr.19:12666887 - 13095486 on Build GRCh38	Deletion	RTBDN RNASEH2A C19orf43 HOOK2 PRDX2 TNPO2 FBXW9 FARSA SNORD135 KLF1 SYCE2 GADD45GIP1 LOC105372280 MIR6794 NFIX CALR MIR5684 MIR5695 BEST2 MAST1 RAD23A WDR83 WDR83OS DHPS DNASE2 JUNB SNORD41 MIR6515 GCDH DAND5 ASNA1
nsv1160586	Chr.19:12597480 - 12823909 on Build GRCh38	Duplication	BEST2 RNASEH2A C19orf43 HOOK2 PRDX2 WDR83 TNPO2 FBXW9 WDR83OS DHPS SNORD135 MAN2B1 JUNB SNORD41 LOC105372280 MIR5684 ZNF791 ZNF490 ASNA1

More Information

Additional Information:

For this assay, SNP(s) [rs73503455] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

endoribonuclease

Gene Ontology Categories:

Process(es)

DNA replication
mismatch repair
RNA catabolic process
DNA replication, removal of RNA primer
RNA phosphodiester bond hydrolysis, endonucleolytic

Function(s)

RNA binding
RNA-DNA hybrid ribonuclease activity
ribonuclease activity
metal ion binding