Hs04241972_cn

• Gene Symbol: FBXL2
• Assay Reference Genome Location: Chr.3:33295031 on build GRCh38
• Cytoband: 3p22.3

Target Gene Details

• Entrez Gene ID: 25827
• Gene Name: F-box and leucine rich repeat protein 2
• Gene Aliases: FBL2, FBL3
• Location: Chr.3:33277422-33422371 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
FBXL2	NM_001171713.1			NP_001165184.1
	NM_012157.3			NP_036289.3
	XM_005265014.2			XP_005265071.1
	XM_005265015.3			XP_005265072.1
	XM_005265016.2			XP_005265073.1
	XM_005265017.3			XP_005265074.1
	XM_011533559.2			XP_011531861.1
	XM_017006092.1			XP_016861581.1
	XM_017006093.1			XP_016861582.1
	XM_017006094.1			XP_016861583.1
	AF174589.1			AAF04510.1
	AF186273.1			AAD56248.1
	AK001271.1
	AK001438.1			BAA91691.1
	AK294209.1
	AK297534.1
	AK298967.1
	AK299665.1
	AK302218.1
	AK303764.1
	AK316229.1
	AK316383.1
	AU124816.1
	BC031556.1			AAH31556.1
	DA031508.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2759138	Chr.3:33253615 - 33429981 on Build GRCh38	Gain	UBP1 FBXL2
nsv834653	Chr.3:33225646 - 33381915 on Build GRCh38	Loss	FBXL2

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

cellular protein modification process
proteolysis
protein monoubiquitination
regulation of autophagy
regulation of phosphatidylinositol 3-kinase signaling
viral process
protein ubiquitination
SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

Function(s)

ubiquitin-protein transferase activity
protein binding
calmodulin binding
protein phosphatase binding
phosphatidylinositol 3-kinase regulatory subunit binding