Hs04293216_cn

• Gene Symbol: PGGT1B
• Assay Reference Genome Location: Chr.5:115206934 on build GRCh38
• Cytoband: 5q22.3

Target Gene Details

• Entrez Gene ID: 5229
• Gene Name: protein geranylgeranyltransferase type I subunit beta
• Gene Aliases: BGGI, GGTI
• Location: Chr.5:115200247-115262887 on Build GRCh38
• Assay Gene Location: Within Exon 9

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PGGT1B	XM_005272020.3	10	6526	XP_005272077.2
	XM_011543490.2			XP_011541792.1
	XM_011543492.2			XP_011541794.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv830454	Chr.5:115118167 - 115271462 on Build GRCh38	Gain+Loss	CCDC112 PGGT1B TRIM36
nsv1029371	Chr.5:115205731 - 115255194 on Build GRCh38	Loss	PGGT1B
nsv830453	Chr.5:114941564 - 115210839 on Build GRCh38	Gain	PGGT1B TRIM36

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

acyltransferase

Gene Ontology Categories:

Process(es)

positive regulation of cell proliferation
protein geranylgeranylation
response to cytokine
positive regulation of cell cycle
negative regulation of nitric-oxide synthase biosynthetic process

Function(s)

protein geranylgeranyltransferase activity
CAAX-protein geranylgeranyltransferase activity
drug binding
zinc ion binding
isoprenoid binding
peptide binding