Hs04459544_cn

• Gene Symbol: GOT2
• Assay Reference Genome Location: Chr.16:58722737 on build GRCh38
• Cytoband: 16q21

Target Gene Details

• Entrez Gene ID: 2806
• Gene Name: glutamic-oxaloacetic transaminase 2
• Gene Aliases: KAT4, KATIV, KYAT4, mitAAT
• Location: Chr.16:58707131-58734357 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
GOT2	NM_001286220.1			NP_001273149.1
	NM_002080.3			NP_002071.2
	AK098313.1
	AK223271.1			BAD96991.1
	AK290847.1
	AK295993.1
	AK302249.1
	AK307598.1
	AL516773.3
	BC000525.2			AAH00525.1
	BI667777.1
	DB485399.1
	M22632.1			AAA35568.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv510686	Chr.16:58612215 - 58731990 on Build GRCh38	Deletion	SLC38A7 GOT2 CNOT1
nsv1065296	Chr.16:58704294 - 58803955 on Build GRCh38	Loss	GOT2
esv2758650	Chr.16:58545101 - 58842133 on Build GRCh38	Loss	SLC38A7 SNORA46 SNORA50A GOT2 CNOT1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

transaminase

Gene Ontology Categories:

Process(es)

gluconeogenesis
2-oxoglutarate metabolic process
oxaloacetate metabolic process
aspartate metabolic process
aspartate biosynthetic process
aspartate catabolic process
glutamate metabolic process
cellular amino acid biosynthetic process
fatty acid transport
4-hydroxyproline catabolic process
glutamate catabolic process to aspartate
glutamate catabolic process to 2-oxoglutarate
response to ethanol
L-kynurenine metabolic process

Function(s)

L-aspartate:2-oxoglutarate aminotransferase activity
phospholipid binding
kynurenine-oxoglutarate transaminase activity
amino acid binding
enzyme binding
pyridoxal phosphate binding
identical protein binding
protein homodimerization activity
poly(A) RNA binding
L-phenylalanine:2-oxoglutarate aminotransferase activity