Hs04544512_cn

• Gene Symbol: RGS8
• Assay Reference Genome Location: Chr.1:182651112 on build GRCh38
• Cytoband: 1q25.3

Target Gene Details

• Entrez Gene ID: 85397
• Gene Name: regulator of G-protein signaling 8
• Gene Aliases: -
• Location: Chr.1:182641814-182753291 on Build GRCh38
• Assay Gene Location: Within Intron 12

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
RGS8	NM_001102450.2			NP_001095920.1
	NM_033345.3			NP_203131.1
	XM_005245555.3			XP_005245612.1
	XM_011510089.2			XP_011508391.1
	XM_011510090.2			XP_011508392.1
	XM_011510091.2			XP_011508393.1
	XM_017002631.1			XP_016858120.1
	XM_017002632.1			XP_016858121.1
	XM_017002633.1			XP_016858122.1
	XM_017002634.1			XP_016858123.1
	XM_017002635.1			XP_016858124.1
	XM_017002636.1			XP_016858125.1
	XM_017002637.1			XP_016858126.1
	AF300649.1			AAG18443.1
	AK294660.1
	AK296514.1
	BC069677.1			AAH69677.1
	BC069718.1			AAH69718.1
	BC103865.1			AAI03866.1
	BC103866.1			AAI03867.1
	BC103867.1			AAI03868.1
	BX281622.1
	BX954018.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv3810	Chr.1:182630610 - 182661590 on Build GRCh38	Deletion	RGS8
nsv548358	Chr.1:182110851 - 183151893 on Build GRCh38	Gain	LAMC1 LINC01344 SHCBP1L ZNF648 RGSL1 GLUL LINC00272 LOC105371644 RGS8 RGS16 TEDDM1 LOC647070 LOC284648 DHX9 NPL RNASEL

More Information

Additional Information:

For this assay, SNP(s) [rs74981986] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

GTPase-activating protein

Gene Ontology Categories:

Process(es)

G-protein coupled acetylcholine receptor signaling pathway
negative regulation of signal transduction
positive regulation of GTPase activity
regulation of dopamine receptor signaling pathway

Function(s)

GTPase activator activity
protein binding