Hs04551226_cn

• Gene Symbol: PKN2
• Assay Reference Genome Location: Chr.1:88689958 on build GRCh38
• Cytoband: 1p22.2

Target Gene Details

• Entrez Gene ID: 5586
• Gene Name: protein kinase N2
• Gene Aliases: PAK2, PRK2, PRKCL2, PRO2042, Pak-2, STK7
• Location: Chr.1:88684144-88836255 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PKN2	NM_001320707.1			NP_001307636.1
	NM_001320708.1			NP_001307637.1
	NM_001320709.1			NP_001307638.1
	NM_006256.3			NP_006247.1
	XM_017001782.1			XP_016857271.1
	XM_017001783.1			XP_016857272.1
	AF118089.2			AAF22033.1
	AK298595.1
	AK300304.1
	BC125199.1
	DA451427.1
	S75548.1			AAB33346.1
	U33052.1			AAC50208.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv546773	Chr.1:88320368 - 88696449 on Build GRCh38	Loss	PKN2-AS1 PKN2

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

transcription, DNA-templated
regulation of transcription, DNA-templated
protein phosphorylation
apoptotic process
cell cycle
signal transduction
epithelial cell migration
peptidyl-serine phosphorylation
positive regulation of cytokinesis
intracellular signal transduction
apical junction assembly
positive regulation of viral genome replication
positive regulation of mitotic cell cycle
cell division
cell-cell adhesion
regulation of cell motility

Function(s)

protein kinase activity
protein serine/threonine kinase activity
protein kinase C activity
protein binding
ATP binding
kinase activity
histone deacetylase binding
poly(A) RNA binding
RNA polymerase binding
cadherin binding involved in cell-cell adhesion