Hs04555811_cn

• Gene Symbol: UBE2F
• Assay Reference Genome Location: Chr.2:237969240 on build GRCh38
• Cytoband: 2q37.3

Target Gene Details

• Entrez Gene ID: 140739
• Gene Name: ubiquitin conjugating enzyme E2 F (putative)
• Gene Aliases: NCE2
• Location: Chr.2:237966945-238042782 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
UBE2F	NM_001278305.1			NP_001265234.1
	NM_001278306.1			NP_001265235.1
	NM_001278307.1			NP_001265236.1
	NM_001278308.1			NP_001265237.1
	NM_080678.2			NP_542409.1
	NR_103498.1
	NR_103499.1
	NR_103500.1
	AK290063.1
	AK293334.1
	AK294107.1
	AK297502.1
	AK303094.1
	BC010549.1			AAH10549.1
	BM920749.1
	BQ959565.1
	BX421077.2
	DA140546.1
	DB118122.1

Target Gene Details

• Entrez Gene ID: 100533179
• Gene Name: UBE2F-SCLY readthrough (NMD candidate)
• Gene Aliases: -
• Location: Chr.2:237966945-238099413 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
UBE2F-SCLY	NR_037904.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv508205	Chr.2:237889539 - 237970025 on Build GRCh38	Deletion	UBE2F RAMP1 UBE2F-SCLY
nsv1000252	Chr.2:235899999 - 238766417 on Build GRCh38	Loss	IQCA1 LOC151174 RAMP1 PER2 SCLY LOC105373958 ERFE ESPNL UBE2F ACKR3 LOC105373944 KLHL30 ASB18 UBE2F-SCLY GBX2 MIR6811 LOC643387 COPS8 LINC01107 MLPH AGAP1 HES6 PRLH ASB1 LOC105373991 LRRFIP1 LOC93463 RAB17 TRAF3IP1 LOC101927958 RBM44 ILKAP COL6A3

More Information

Additional Information:

For this assay, SNP(s) [rs115164308] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

ubiquitin-protein ligase

Gene Ontology Categories:

Process(es)

postreplication repair
protein neddylation
protein K63-linked ubiquitination

Function(s)

protein binding
ATP binding
ligase activity
NEDD8 transferase activity
ubiquitin protein ligase binding
ubiquitin protein ligase activity