Hs04562364_cn

• Gene Symbol: CD8B
• Assay Reference Genome Location: Chr.2:86833099 on build GRCh38
• Cytoband: 2p11.2

Target Gene Details

• Entrez Gene ID: 926
• Gene Name: CD8b molecule
• Gene Aliases: CD8B1, LEU2, LY3, LYT3, P37
• Location: Chr.2:86815337-86861924 on Build GRCh38
• Assay Gene Location: Within Intron 6

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CD8B	NM_001178100.1			NP_001171571.1
	NM_172101.3			NP_742099.1
	NM_172102.3			NP_742100.1
	NM_172213.3			NP_757362.1
	BC100911.1			AAI00912.1
	BC100912.2			AAI00913.1
	BC100913.1			AAI00914.1
	BC100914.1			AAI00915.1
	BQ004743.1
	X13445.1			CAA31796.1
	X13446.1			CAA31797.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv10063	Chr.2:86713865 - 86857237 on Build GRCh38	Gain	CD8A RMND5A CD8B RNF103-CHMP3
dgv714e214	Chr.2:86745573 - 86951144 on Build GRCh38	Gain	CD8A ANAPC1P1 RMND5A RGPD1 CD8B
esv25494	Chr.2:86745091 - 86946998 on Build GRCh38	Gain	CD8A ANAPC1P1 RMND5A RGPD1 CD8B
nsv458585	Chr.2:86747195 - 86881088 on Build GRCh38	Gain	CD8A ANAPC1P1 RMND5A CD8B
nsv997982	Chr.2:86745711 - 86878741 on Build GRCh38	Gain	CD8A ANAPC1P1 RMND5A CD8B
dgv3886n100	Chr.2:86721712 - 86945592 on Build GRCh38	Gain	CD8A ANAPC1P1 RMND5A RGPD1 CD8B

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

defense/immunity protein, immunoglobulin receptor superfamily

Gene Ontology Categories:

Process(es)

adaptive immune response
immune response
transmembrane receptor protein tyrosine kinase signaling pathway
T cell activation
regulation of defense response to virus by virus
regulation of immune response

Function(s)

protein binding
coreceptor activity
MHC class I protein binding