Hs04590249_cn

• Gene Symbol: SCLY
• Assay Reference Genome Location: Chr.2:238062875 on build GRCh38
• Cytoband: 2q37.3

Target Gene Details

• Entrez Gene ID: 51540
• Gene Name: selenocysteine lyase
• Gene Aliases: SCL, hSCL
• Location: Chr.2:238060924-238099413 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SCLY	NM_016510.5			NP_057594.4
	AB209458.2			BAD92695.1
	AF175767.1			AAF36816.1
	AK293283.1
	AK298409.1
	AK301009.1
	BC000586.2			AAH00586.2
	BC007891.2			AAH07891.1
	DN995828.1

Target Gene Details

• Entrez Gene ID: 100533179
• Gene Name: UBE2F-SCLY readthrough (NMD candidate)
• Gene Aliases: -
• Location: Chr.2:237966945-238099413 on Build GRCh38
• Assay Gene Location: Within Intron 8

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
UBE2F-SCLY	NR_037904.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv4193n100	Chr.2:237988669 - 238064519 on Build GRCh38	Gain	UBE2F-SCLY UBE2F SCLY
nsv1000252	Chr.2:235899999 - 238766417 on Build GRCh38	Loss	ERFE ACKR3 LRRFIP1 KLHL30 COPS8 LOC105373958 LINC01107 PER2 IQCA1 PRLH RAB17 ASB1 LOC101927958 RBM44 RAMP1 LOC643387 ASB18 GBX2 AGAP1 ESPNL LOC105373991 ILKAP MIR6811 HES6 SCLY LOC105373944 UBE2F-SCLY LOC151174 COL6A3 UBE2F TRAF3IP1 MLPH LOC93463

More Information

Additional Information:

For this assay, SNP(s) [rs73098309] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

lyase, metabolite interconversion enzyme

Gene Ontology Categories:

Process(es)

selenium compound metabolic process
cellular amino acid metabolic process

Function(s)

protein binding
selenocysteine lyase activity
transferase activity