Hs04602211_cn

• Gene Symbol: FBLN7
• Assay Reference Genome Location: Chr.2:112218370 on build GRCh38
• Cytoband: 2q14.1

Target Gene Details

• Entrez Gene ID: 129804
• Gene Name: fibulin 7
• Gene Aliases: TM14
• Location: Chr.2:112138385-112254888 on Build GRCh38
• Assay Gene Location: Within Intron 10

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
FBLN7	XM_017003317.1			XP_016858806.1
	XM_017003318.1			XP_016858807.1

Target Gene Details

• Entrez Gene ID: 84524
• Gene Name: zinc finger CCCH-type containing 8
• Gene Aliases: Fliz1, ZC3HDC8
• Location: Chr.2:112215035-112255087 on Build GRCh38
• Assay Gene Location: Within Intron 10

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ZC3H8	NM_032494.2			NP_115883.2
	XM_011511998.1			XP_011510300.1
	XM_017005107.1			XP_016860596.1
	AF334161.1			AAK13496.1
	BC032001.1			AAH32001.1
	CV574571.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv521956	Chr.2:110634682 - 112341235 on Build GRCh38	Loss	MIR4771-2 MIR4435-2HG PAFAH1B1P2 LOC400997 ZC3H8 MIR4435-2 TMEM87B BCL2L11 SNORD132 BUB1 ZC3H6 ACOXL ANAPC1 MERTK FBLN7
nsv582703	Chr.2:112162642 - 112342437 on Build GRCh38	Loss	ZC3H6 ZC3H8 FBLN7
dgv4047n100	Chr.2:110308696 - 112358403 on Build GRCh38	Loss	MIR4771-2 MIR4435-2HG PAFAH1B1P2 LOC400997 ZC3H8 MIR4435-2 TMEM87B LOC100288570 BCL2L11 RGPD6 LOC105375809 SNORD132 BUB1 LOC105373553 ZC3H6 ACOXL LINC01106 ANAPC1 MERTK LIMS4 FBLN7

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

extracellular matrix structural protein, zinc finger transcription factor

Gene Ontology Categories:

Process(es)

cell adhesion
negative regulation of transcription from RNA polymerase II promoter
apoptotic process
negative regulation of T cell differentiation in thymus
snRNA transcription from RNA polymerase II promoter
snRNA transcription from RNA polymerase III promoter
T cell homeostasis
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase III promoter
response to antibiotic
positive regulation of thymocyte apoptotic process

Function(s)

calcium ion binding
heparin binding
RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
protein binding
sequence-specific DNA binding
poly(A) RNA binding
metal ion binding