Hs04642720_cn

• Gene Symbol: SOS1
• Assay Reference Genome Location: Chr.2:38981657 on build GRCh38
• Cytoband: 2p22.1

Target Gene Details

• Entrez Gene ID: 6654
• Gene Name: SOS Ras/Rac guanine nucleotide exchange factor 1
• Gene Aliases: GF1, GGF1, GINGF, HGF, NS4
• Location: Chr.2:38981549-39124959 on Build GRCh38
• Assay Gene Location: Within Exon 26

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SOS1	NM_005633.3	23	8210	NP_005624.2
	AV702692.1	1	548

More Information

• Set Membership: Intragenic, Exonic, non-DGV Variation

Panther Classification:

Molecular Function -

guanyl-nucleotide exchange factor

Gene Ontology Categories:

Process(es)

MAPK cascade
B cell homeostasis
hair follicle development
cardiac atrium morphogenesis
pericardium morphogenesis
signal transduction
epidermal growth factor receptor signaling pathway
Ras protein signal transduction
vitellogenesis
axon guidance
insulin receptor signaling pathway
regulation of T cell differentiation in thymus
regulation of Rho protein signal transduction
multicellular organism growth
Fc-epsilon receptor signaling pathway
ERBB2 signaling pathway
regulation of T cell proliferation
positive regulation of apoptotic process
positive regulation of GTPase activity
positive regulation of epidermal growth factor receptor signaling pathway
neurotrophin TRK receptor signaling pathway
blood vessel morphogenesis
leukocyte migration
regulation of small GTPase mediated signal transduction
positive regulation of small GTPase mediated signal transduction
palate development
eyelid development in camera-type eye
heart trabecula morphogenesis
midbrain morphogenesis
regulation of pro-B cell differentiation

Function(s)

DNA binding
guanyl-nucleotide exchange factor activity
Ras guanyl-nucleotide exchange factor activity
Rho guanyl-nucleotide exchange factor activity
GTPase activator activity
protein binding
SH3 domain binding
protein heterodimerization activity