Hs04660671_cn

• Gene Symbol: IL1A
• Assay Reference Genome Location: Chr.2:112776369 on build GRCh38
• Cytoband: 2q14.1

Target Gene Details

• Entrez Gene ID: 3552
• Gene Name: interleukin 1 alpha
• Gene Aliases: IL-1A, IL1, IL1-ALPHA, IL1F1
• Location: Chr.2:112773915-112785398 on Build GRCh38
• Assay Gene Location: Within Intron 6

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
IL1A	NM_000575.4			NP_000566.3
	AK314850.1
	BC013142.2			AAH13142.1
	BT007014.1			AAP35660.1
	CR457414.1			CAG33695.1
	M15329.1			AAA59133.1
	X02531.1			CAA26371.1
	X02851.1			CAA26604.1
	X56086.1			CAA39566.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2720538	Chr.2:112775968 - 112777350 on Build GRCh38	Deletion	IL1A
nsv1072437	Chr.2:112776322 - 112777223 on Build GRCh38	Deletion	IL1A
esv2720540	Chr.2:112776219 - 112777147 on Build GRCh38	Deletion	IL1A
esv2518569	Chr.2:112776018 - 112777424 on Build GRCh38	Deletion	IL1A

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

interleukin superfamily

Gene Ontology Categories:

Process(es)

fever generation
connective tissue replacement involved in inflammatory response wound healing
apoptotic process
inflammatory response
immune response
cell proliferation
negative regulation of cell proliferation
positive regulation of vascular endothelial growth factor production
positive regulation of gene expression
cytokine-mediated signaling pathway
cellular response to heat
ectopic germ cell programmed cell death
positive regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of interleukin-2 biosynthetic process
positive regulation of angiogenesis
positive regulation of mitotic nuclear division
positive regulation of transcription from RNA polymerase II promoter
positive regulation of JNK cascade
response to copper ion
positive regulation of protein secretion
positive regulation of cytokine secretion
positive regulation of cell division
extrinsic apoptotic signaling pathway in absence of ligand
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

Function(s)

cytokine activity
interleukin-1 receptor binding
copper ion binding
protein binding